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Flinders Academic Commons >
Browsing by Author Elliot, David John
Showing results 1 to 20 of 21
| Preview | Issue Date | Title | Author(s) | | 2008 | The "Albumin Effect" and in Vitro-in
Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances
Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450
2C9 | Mackenzie, Peter Ian; Miners, John Oliver; Rowland, Andrew; Elliot, David John; Knights, Kathleen Mary |
| 2007 | Amino terminal domains of human
UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity
and autoactivation | Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Elliot, David John; Burchell, Brian; Bhasker, Ramana; Miners, John Oliver |
| 2007 | Binding of inhibitory fatty acids is responsible
for the enhancement of UDP-Glucuronosyltransferase 2B7 activity by albumin: implications
for in vitro-in vivo extrapolation | Rowland, Andrew; Miners, John Oliver; Gaganis, Paraskevi; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary |
| 2007 | Critical roles of residues 36 and 40 in the phenol
and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3
and 1A4 | Kubota, Takahiro; Mackenzie, Peter Ian; Miners, John Oliver; Lewis, Benjamin Cavell; Elliot, David John |
| 2004 | Differential contribution of active site residues
in substrate recognition sites 1 and 5 to cytochrome P450 2C8 substrate selectivity and
regioselectivity | Yoovathaworn, Krontong; Kerdpin, Oranun; Miners, John Oliver; Boye, S; Birkett, Donald John; Elliot, David John |
| 2005 | Electrochemical characterisation of the human
cytochrome P450 CYP2C9 | Lewis, Benjamin Cavell; Johnson, D L; Miners, John Oliver; Martin, L L; Elliot, David John |
| 2006 | An evaluation of potential mechanism-based
inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase
inhibitors, including isoniazid | Polasek, Thomas Metodey; Elliot, David John; Somogyi, Andrew A; Gillam, Elizabeth M J; Lewis, Benjamin Cavell; Miners, John Oliver |
| 2007 | The glucuronidation of delta4-3-keto C19- and
C21-hydroxysteroids by human liver microsomal and recombinant
UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective
substrates for UGT2B7 | Bowalgaha Ralalage, Kushari Wathsala; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary; Miners, John Oliver |
| 2007 | Identification of the human cytochromes P450
catalysing the rate-limiting pathways of gliclazide elimination | Miners, John Oliver; Suharjono, M S; Lewis, Benjamin Cavell; Gillam, Elizabeth M J; Birkett, Donald John; Gross, A; Elliot, David John |
| 2007 | Influence of mutations associated with Gilbert and
Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other
UDP-glucuronosyltransferase 1A substrates | Elliot, David John; Miners, John Oliver; Udomuksorn, Wandee; Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Yoovathaworn, Krontong |
| 2008 | In vitro characterisation of human renal and
hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase
enzymes involved in this pathway | Kerdpin, Oranun; Knights, Kathleen Mary; Elliot, David John; Miners, John Oliver |
| 2006 | In vitro characterization of lamotrigine
N2-glucuronidation and the lamotrigine-valproic acid interaction | Rowland, Andrew; Elliot, David John; Williams, Andrew; Mackenzie, Peter Ian; Dickinson, Ronald G; Miners, John Oliver |
| 2007 | In vitro-in vivo extrapolation of drug
glucuronidation kinetic parameters: Pitfalls and Promises | Miners, John Oliver; Rowland, Andrew; Uchaipichat, Verawan Nu; Elliot, David John; Knights, Kathleen Mary; Galetin, A; Houston, J Brian; Mackenzie, Peter Ian |
| 2006 | Measurement of Human Cytochrome P4501A2 (CYP1A2)
Activity in Vitro | Polasek, Thomas Metodey; Elliot, David John; Miners, John Oliver |
| 2004 | Mechanism-based inactivation of human cytochrome
PO4502C8 by drugs in vitro | Polasek, Thomas Metodey; Lewis, Benjamin Cavell; Miners, John Oliver; Elliot, David John |
| 2004 | Optimizing bacterial expression of catalytically
active human cytochromes P450: comparison of CYP2C8 and CYP2C9 | Yoovathaworn, Krontong; Kerdpin, Oranun; Miners, John Oliver; Boye, S; Bhasker, Ramana; Birkett, Donald John; Elliot, David John; Kelly, L; McKinnon, Ross A |
| 2006 | Quantitative prediction of in vivo inhibitory
interactions involving glucuronidated drugs from in vitro data: the effect of
fluconazole on zidovudine glucuronidation | Winner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu |
| 2006 | Selectivity of substrate (trifluoperazine) and
inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone,
quinidine, quinine, and sulfinpyrazone) 'probes' for human
UDP-glucuronosyltransferases | Uchaipichat, Verawan Nu; Mackenzie, Peter Ian; Elliot, David John; Miners, John Oliver |
| 2005 | S-Naproxen and desmethylnaproxen glucuronidation
by human liver miscrosomes and recombinant human UDP-glucuronosyltransferases (UGT):
role of UGT2B7 in the elimination of naproxen | Bowalgaha Ralalage, Kushari Wathsala; Mackenzie, Peter Ian; Knights, Kathleen Mary; Swedmark, S; Miners, John Oliver; Elliot, David John |
| 2006 | Sulfinpyrazone C-Glucuronidation Is Catalyzed
Selectively by Human UDP-Glucuronosyltransferase 1A9 | Kerdpin, Oranun; Elliot, David John; Mackenzie, Peter Ian; Miners, John Oliver |
Showing results 1 to 20 of 21
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