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Browsing by Author Elliot, David John

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PreviewIssue DateTitleAuthor(s)
2007Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4Kubota, Takahiro; Mackenzie, Peter Ian; Miners, John Oliver; Lewis, Benjamin Cavell; Elliot, David John
2004Differential contribution of active site residues in substrate recognition sites 1 and 5 to cytochrome P450 2C8 substrate selectivity and regioselectivityYoovathaworn, Krontong; Kerdpin, Oranun; Miners, John Oliver; Boye, S; Birkett, Donald John; Elliot, David John
2005Electrochemical characterisation of the human cytochrome P450 CYP2C9Lewis, Benjamin Cavell; Johnson, D L; Miners, John Oliver; Martin, L L; Elliot, David John
2006An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazidPolasek, Thomas Metodey; Elliot, David John; Somogyi, Andrew A; Gillam, Elizabeth M J; Lewis, Benjamin Cavell; Miners, John Oliver
2007The glucuronidation of delta4-3-keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7Bowalgaha Ralalage, Kushari Wathsala; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary; Miners, John Oliver
2007Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide eliminationMiners, John Oliver; Suharjono, M S; Lewis, Benjamin Cavell; Gillam, Elizabeth M J; Birkett, Donald John; Gross, A; Elliot, David John
2007Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substratesElliot, David John; Miners, John Oliver; Udomuksorn, Wandee; Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Yoovathaworn, Krontong
2008In vitro characterisation of human renal and hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase enzymes involved in this pathwayKerdpin, Oranun; Knights, Kathleen Mary; Elliot, David John; Miners, John Oliver
2006In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interactionRowland, Andrew; Elliot, David John; Williams, Andrew; Mackenzie, Peter Ian; Dickinson, Ronald G; Miners, John Oliver
2007In vitro-in vivo extrapolation of drug glucuronidation kinetic parameters: Pitfalls and PromisesMiners, John Oliver; Rowland, Andrew; Uchaipichat, Verawan Nu; Elliot, David John; Knights, Kathleen Mary; Galetin, A; Houston, J Brian; Mackenzie, Peter Ian
2006Measurement of Human Cytochrome P4501A2 (CYP1A2) Activity in VitroPolasek, Thomas Metodey; Elliot, David John; Miners, John Oliver
2004Mechanism-based inactivation of human cytochrome PO4502C8 by drugs in vitroPolasek, Thomas Metodey; Lewis, Benjamin Cavell; Miners, John Oliver; Elliot, David John
2004Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9Yoovathaworn, Krontong; Kerdpin, Oranun; Miners, John Oliver; Boye, S; Bhasker, Ramana; Birkett, Donald John; Elliot, David John; Kelly, L; McKinnon, Ross A
2006Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationWinner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu
2006Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) 'probes' for human UDP-glucuronosyltransferasesUchaipichat, Verawan Nu; Mackenzie, Peter Ian; Elliot, David John; Miners, John Oliver
2005S-Naproxen and desmethylnaproxen glucuronidation by human liver miscrosomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxenBowalgaha Ralalage, Kushari Wathsala; Mackenzie, Peter Ian; Knights, Kathleen Mary; Swedmark, S; Miners, John Oliver; Elliot, David John
2006Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9Kerdpin, Oranun; Elliot, David John; Mackenzie, Peter Ian; Miners, John Oliver
2003Variable photosynthetic characteristics in waste stabilisation ponds .Weatherall, C A; Fallowfield, Howard John; Elliot, David John; Curtis, T P
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