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Browsing by Author Mackenzie, Peter Ian

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PreviewIssue DateTitleAuthor(s)
1-Dec-2012Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.Korprasertthaworn, P; Rowland, Andrew; Lewis, BC; Mackenzie, Peter Ian; Yoovathaworn, K; Miners, John Oliver
2006Fatty acyl-CoA as an endogenous activator of UDP-glucuronosyltransferasesOkamura, Kazuharu; Ishii, Yuji; Ikushiro, Shin-ichi; Mackenzie, Peter Ian; Yamada, Hideyuki
2003Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.Mackenzie, Peter Ian; Radominska-Pandya, A; Little, J M
2004Glucuronidation and the UDP-glucuronosyltransferases in health and diseaseWells, P G; Hansen, A J; Gregory, Philip A; Ishii, Yuji; Mackenzie, Peter Ian; Guillemette, Chantal; Chowdhury, J R; Choudhury, Namita R; Kessler, F K; Kim, P M; Ritter, J K
2005Glucuronidation of bioflavonoids by human UGT1A10: structure-function relationshipsLewinsky, Rikke Holm; Smith, Paul Alexander; Mackenzie, Peter Ian
2007The glucuronidation of delta4-3-keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7Bowalgaha Ralalage, Kushari Wathsala; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary; Miners, John Oliver
2007Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alphaGardner-Stephen, Dione Anne; Mackenzie, Peter Ian
2004Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expressionXie, W; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Radominska-Pandya, A; Goyal, A; Heydel, J M; Lindblom, T; Lu, Y
2005Human UDP-glucuronosyltransferase 1A5: indentification, expression and activityFinel, Moshe; Li, X; Gardner-Stephen, Dione Anne; Bratton, S; Mackenzie, Peter Ian; Radominska-Pandya, A
10-Jul-2012Human UDP-Glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal His-tag on glucuronidation kineticsZhang, Hongbo; Patana, Anne-Sisko; Mackenzie, Peter Ian; Ikushiro, Shin-ichi; Goldman, Adrian; Finel, Moshe
2004Human UDP-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumberlliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecidGuo, X H; Uchaipichat, Verawan Nu; Miners, John Oliver; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Galetin, A; Houston, J Brian
2005Identification and characterization of functional hepatocyte nuclear factor 1-binding sites in UDP-glucuronosyltransferase genesGregory, Philip A; Gardner-Stephen, Dione Anne; Mackenzie, Peter Ian
2008Identification of UDP Glycosyltransferase 3A1 as a UDP N-AcetylglucosaminyltransferaseMackenzie, Peter Ian; Rogers, Anne; Jorgensen, B R; Miners, John Oliver; Meech, Robyn; Gillis, Joanna Lee
2007Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substratesElliot, David John; Miners, John Oliver; Udomuksorn, Wandee; Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Yoovathaworn, Krontong
8-Aug-2012Inhibition of morphine glucuronidation in the liver microsomes of rats and humans by monoterpenoid alcoholsIshii, Yuji; Iida, Naoko; Miyauchi, Yuu; Mackenzie, Peter Ian; Yamada, Hideyuki
2006Inhibition of UDP-glucuronosyltransferase 2B7-catalyzed morphine glucuronidation by Ketoconazole: Dual mechanisms involving a novel non-competitive modeTakeda, Shuso; Kitajima, Yurie; Ishii, Yuji; Nishimura, Yoshio; Mackenzie, Peter Ian; Oguri, Kazuta; Yamada, Hideyuki
2007Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: structure-effect relationships and evidence for an allosteric mechanismYamada, Hideyuki; Maeda, Shingo; Ikushiro, Shin-ichi; Mackenzie, Peter Ian; Ishii, Yuji; Nishimura, Yoshio
2007Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6Court, M H; Tate, Christopher G; Hirvonen, Jouni; Kurkela, Mika; Patana, Anne-Sisko; Mackenzie, Peter Ian; Goldman, Adrian; Finel, Moshe
2006In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interactionRowland, Andrew; Elliot, David John; Williams, Andrew; Mackenzie, Peter Ian; Dickinson, Ronald G; Miners, John Oliver
2006In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: Pitfalls and promisesMiners, John Oliver; Knights, Kathleen Mary; Houston, J Brian; Mackenzie, Peter Ian
Showing results 14 to 33 of 54
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