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Flinders Academic Commons >
Browsing by Author Mackenzie, Peter Ian
Showing results 23 to 42 of 47
| Preview | Issue Date | Title | Author(s) | | 2007 | Influence of mutations associated with Gilbert and
Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other
UDP-glucuronosyltransferase 1A substrates | Elliot, David John; Miners, John Oliver; Udomuksorn, Wandee; Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Yoovathaworn, Krontong |
| 2006 | Inhibition of UDP-glucuronosyltransferase
2B7-catalyzed morphine glucuronidation by Ketoconazole: Dual mechanisms involving a
novel non-competitive mode | Takeda, Shuso; Kitajima, Yurie; Ishii, Yuji; Nishimura, Yoshio; Mackenzie, Peter Ian; Oguri, Kazuta; Yamada, Hideyuki |
| 2007 | Inhibitory effects of adenine nucleotides and
related substances on UDP-glucuronosyltransferase: structure-effect relationships and
evidence for an allosteric mechanism | Yamada, Hideyuki; Maeda, Shingo; Ikushiro, Shin-ichi; Mackenzie, Peter Ian; Ishii, Yuji; Nishimura, Yoshio |
| 2007 | Interactions with other human
UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the
activity and substrate affinity of UGT1A6 | Court, M H; Tate, Christopher G; Hirvonen, Jouni; Kurkela, Mika; Patana, Anne-Sisko; Mackenzie, Peter Ian; Goldman, Adrian; Finel, Moshe |
| 2006 | In vitro characterization of lamotrigine
N2-glucuronidation and the lamotrigine-valproic acid interaction | Rowland, Andrew; Elliot, David John; Williams, Andrew; Mackenzie, Peter Ian; Dickinson, Ronald G; Miners, John Oliver |
| 2006 | In vitro-in vivo correlation for drugs and other
compounds eliminated by glucuronidation in humans: Pitfalls and promises | Miners, John Oliver; Knights, Kathleen Mary; Houston, J Brian; Mackenzie, Peter Ian |
| 2007 | In vitro-in vivo extrapolation of drug
glucuronidation kinetic parameters: Pitfalls and Promises | Miners, John Oliver; Rowland, Andrew; Uchaipichat, Verawan Nu; Elliot, David John; Knights, Kathleen Mary; Galetin, A; Houston, J Brian; Mackenzie, Peter Ian |
| 2003 | Isoform selectivity and kinetics of morphine 3-
and 6-glucuronidation by human UDP-glucuronosyltranferases: evidence for atypical
glucuronidation kinetics by UGT2B7. | Stone, A N; Miners, John Oliver; Mackenzie, Peter Ian; Galetin, A; Houston, J Brian |
| 2007 | Isolation of the UDP-glucuronosyltransferase 1A3
and 1A4 proximal promoters and characterization of their dependence on the transcription
factor hepatocyte nuclear factor 1 alpha | Gardner-Stephen, Dione Anne; Mackenzie, Peter Ian |
| 2008 | Kinetic modeling of the interactions between
4-Methylumbelliferone, 1-Naphthol, and zidovudine glucuronidation by
UDP-glucuronosyltransferase 2B7 (UGT2B7) provides evidence for multiple substrate
binding and effector sites | Galetin, A; Mackenzie, Peter Ian; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu; Houston, J Brian |
| 2008 | Liver-enriched transcription factors and their
role in regulating UDP glucuronosyltransferase gene expression | Gardner-Stephen, Dione Anne; Mackenzie, Peter Ian |
| 2005 | Modulation of UDP-glucuronosyltransferase 2B7
function by cytochrome P450s in vitro: Differential effects of CYP1A2, CYP2C9 and
CYP3A4 | Takeda, Shuso; Ishii, Yuji; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki |
| 2005 | Modulation of UDP-glucuronosyltransferase function
by cytochrome P450: Evidence for the alteration of UGT2B7-catalyzed glucuronidation of
morphine by CYP3A4 | Takeda, Shuso; Ishii, Yuji; Iwanaga, Megumi; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki |
| 2005 | Polymorphic variations in the expression of the
chemical detoxifying UDP glucuronosytransferases | Mackenzie, Peter Ian; Gregory, Philip A; Lewinsky, Rikke Holm; Yasmin, S N; Height, T; MacKinnon, R A; Gardner-Stephen, Dione Anne |
| 2004 | Predicating Human Drug Glucuronidation Parameters:
Application of In Vitro and InSilico Modeling Approaches | Smith, Paul Alexander; Miners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J |
| 2006 | Quantitative prediction of in vivo inhibitory
interactions involving glucuronidated drugs from in vitro data: the effect of
fluconazole on zidovudine glucuronidation | Winner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu |
| 2008 | Recent advances in the in silico modelling of UDP
Glucuronosyltransferase Substrates | Miners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J; Smith, Paul Alexander |
| 2003 | Regulation of UDP glucuronosyltransferase
genes. | Nishiyama, T; Xie, W; Gregory, Philip A; Lewinsky, Rikke Holm; Jorgensen, B R; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Radominska-Pandya, A |
| 2004 | Regulation of UDP-glucuronosyltransferases in the
gastrointestinal tract | Gregory, Philip A; Lewinsky, Rikke Holm; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne |
| 2006 | Relationship between hyperbilirubinaemia and
UDP-glucoronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai
patients treated with indinavir | Boyd, Mark Alastair; Srasuebkul, Preeyaporn; Ruxrungtham, Kiat; Uchaipichat, Verawan Nu; Mackenzie, Peter Ian; Stek, Michael; Lange, Joep M A; Phanuphak, Praphan; Cooper, David A; Udomuksorn, Wandee; Miners, John Oliver |
Showing results 23 to 42 of 47
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