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Browsing by Author Mackenzie, Peter Ian

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PreviewIssue DateTitleAuthor(s)
2007Binding of inhibitory fatty acids is responsible for the enhancement of UDP-Glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolationRowland, Andrew; Miners, John Oliver; Gaganis, Paraskevi; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary
2007Carboxylic Acid Drug-Induced DNA Nicking in HEK293 Cells Expressing Human UDP-Glucuronosyltransferases: Role of Acyl Glucuronide Metabolites and Glycation PathwaysMackenzie, Peter Ian; DeGraaf, Yvette; Southwood, H; Burcham, P; Miners, John Oliver; Sallustio, B
2006The caudal-related homeodomain protein Cdx2 and hepatocyte nuclear factor 1-alpha cooperatively regulate the UDP-glucuronosyltransferase 2B7 gene promotorGregory, Philip A; Gardner-Stephen, Dione Anne; Rogers, Anne; Michael, Michael Zenon; Mackenzie, Peter Ian
2009Characterization of the Binding of Drugs to Human Intestinal Fatty Acid Binding Protein (IFABP): Potential Role of IFABP as an Altenative to Albumin for in Vitro-in Vivo Extrapolation of Drug Kinetic ParametersRowland, Andrew; Knights, Kathleen Mary; Mackenzie, Peter Ian; Miners, John Oliver
2003Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an intitiator-like region.Gregory, Philip A; Lewinsky, Rikke Holm; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Duncliffe, K N
2007Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysisMiners, John Oliver; Lewis, Benjamin Cavell; Mackenzie, Peter Ian
2008The configuration of the 17-hydroxy group variably influences the glucuronidation of B-estradiol and epiestradiol by human UDP-GlucuronosyltransferasesItaaho, Katrina; Mackenzie, Peter Ian; Ikushiro, Shin-ichi; Miners, John Oliver; Finel, Moshe
2004Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9 and 1A10 genes by hepatocyte nuclear factor 1-alpha and the caudal-related homeodomain protein 2Gregory, Philip A; Lewinsky, Rikke Holm;