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Browsing by Author Mackenzie, Peter Ian

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PreviewIssue DateTitleAuthor(s)
2008Kinetic modeling of the interactions between 4-Methylumbelliferone, 1-Naphthol, and zidovudine glucuronidation by UDP-glucuronosyltransferase 2B7 (UGT2B7) provides evidence for multiple substrate binding and effector sitesGaletin, A; Mackenzie, Peter Ian; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu; Houston, J Brian
2008Liver-enriched transcription factors and their role in regulating UDP glucuronosyltransferase gene expressionGardner-Stephen, Dione Anne; Mackenzie, Peter Ian
2005Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: Differential effects of CYP1A2, CYP2C9 and CYP3A4Takeda, Shuso; Ishii, Yuji; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki
2005Modulation of UDP-glucuronosyltransferase function by cytochrome P450: Evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4Takeda, Shuso; Ishii, Yuji; Iwanaga, Megumi; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki
2005Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosytransferasesMackenzie, Peter Ian; Gregory, Philip A; Lewinsky, Rikke Holm; Yasmin, S N; Height, T; MacKinnon, R A; Gardner-Stephen, Dione Anne
2004Predicating Human Drug Glucuronidation Parameters: Application of In Vitro and InSilico Modeling ApproachesSmith, Paul Alexander; Miners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J
2006Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationWinner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu
2008Recent advances in the in silico modelling of UDP Glucuronosyltransferase Substrates