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Browsing by Author Mackenzie, Peter Ian

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PreviewIssue DateTitleAuthor(s)
2005Modulation of UDP-glucuronosyltransferase 2B7 function by cytochrome P450s in vitro: Differential effects of CYP1A2, CYP2C9 and CYP3A4Takeda, Shuso; Ishii, Yuji; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki
2005Modulation of UDP-glucuronosyltransferase function by cytochrome P450: Evidence for the alteration of UGT2B7-catalyzed glucuronidation of morphine by CYP3A4Takeda, Shuso; Ishii, Yuji; Iwanaga, Megumi; Mackenzie, Peter Ian; Nagata, Kiyoshi; Yamazoe, Yasushi; Oguri, Kazuta; Yamada, Hideyuki
2005Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamilyBurchell, Brian; Guillemette, Chantal; Iyanagi, T; Miners, John Oliver; Owens, Ida S; Nerbert, Daniel W; Ikushiro, S; Mackenzie, Peter Ian; Bock, Karl Walter
2010A Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and is associated with altered levels of circulating Androstane-3{alpha},17{beta}-diol GlucuronideHu, Dong Gui; Gardner-Stephen, Dione Anne; Severi, G; Gregory, P A; Treloar, Joanna; Giles, G G; Hopper, John L; Tilley, Wayne; English, Dallas; Mackenzie, Peter Ian
2005Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosytransferasesMackenzie, Peter Ian; Gregory, Philip A; Lewinsky, Rikke Holm; Yasmin, S N; Height, T; MacKinnon, R A; Gardner-Stephen, Dione Anne
May-2014Polymorphisms and Haplotypes of the UDP-Glucuronosyltransferase 2B7 Gene PromoterHu, Dong; Meech, Robyn; Lu, Lu; McKinnon, Ross A; Mackenzie, Peter Ian
2004Predicating Human Drug Glucuronidation Parameters: Application of In Vitro and InSilico Modeling ApproachesSmith, Paul Alexander; Miners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J
2010The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potentialMiners, John Oliver; Mackenzie, Peter Ian; Knights, Kathleen Mary
2006Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationWinner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu
2008Recent advances in the in silico modelling of UDP Glucuronosyltransferase SubstratesMiners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J; Smith, Paul Alexander
2003Regulation of UDP glucuronosyltransferase genes.Nishiyama, T; Xie, W; Gregory, Philip A; Lewinsky, Rikke Holm; Jorgensen, B R; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Radominska-Pandya, A
2010The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factorsHu, Dong Gui; Gardner-Stephen, Dione Anne; Mackenzie, Peter Ian
2004Regulation of UDP-glucuronosyltransferases in the gastrointestinal tractGregory, Philip A; Lewinsky, Rikke Holm; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne
2006Relationship between hyperbilirubinaemia and UDP-glucoronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai patients treated with indinavirBoyd, Mark Alastair; Srasuebkul, Preeyaporn; Ruxrungtham, Kiat; Uchaipichat, Verawan Nu; Mackenzie, Peter Ian; Stek, Michael; Lange, Joep M A; Phanuphak, Praphan; Cooper, David A; Udomuksorn, Wandee; Miners, John Oliver
2006Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, andros