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Browsing by Author Mackenzie, Peter Ian

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PreviewIssue DateTitleAuthor(s)
2010A Novel Polymorphism in a Forkhead Box A1 (FOXA1) Binding Site of the Human UDP Glucuronosyltransferase 2B17 Gene Modulates Promoter Activity and is associated with altered levels of circulating Androstane-3{alpha},17{beta}-diol GlucuronideHu, Dong Gui; Gardner-Stephen, Dione Anne; Severi, G; Gregory, P A; Treloar, Joanna; Giles, G G; Hopper, John L; Tilley, Wayne; English, Dallas; Mackenzie, Peter Ian
2005Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosytransferasesMackenzie, Peter Ian; Gregory, Philip A; Lewinsky, Rikke Holm; Yasmin, S N; Height, T; MacKinnon, R A; Gardner-Stephen, Dione Anne
May-2014Polymorphisms and Haplotypes of the UDP-Glucuronosyltransferase 2B7 Gene PromoterHu, Dong; Meech, Robyn; Lu, Lu; McKinnon, Ross A; Mackenzie, Peter Ian
2004Predicating Human Drug Glucuronidation Parameters: Application of In Vitro and InSilico Modeling ApproachesSmith, Paul Alexander; Miners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J
2010The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potentialMiners, John Oliver; Mackenzie, Peter Ian; Knights, Kathleen Mary
2006Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidationWinner, Leanne; Mackenzie, Peter Ian; Elliot, David John; Williams, Andrew; Miners, John Oliver; Uchaipichat, Verawan Nu
2008Recent advances in the in silico modelling of UDP Glucuronosyltransferase SubstratesMiners, John Oliver; Mackenzie, Peter Ian; McKinnon, Ross A; Sorich, Michael J; Smith, Paul Alexander
2003Regulation of UDP glucuronosyltransferase genes.Nishiyama, T; Xie, W; Gregory, Philip A; Lewinsky, Rikke Holm; Jorgensen, B R; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne; Radominska-Pandya, A
2010The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factorsHu, Dong Gui; Gardner-Stephen, Dione Anne; Mackenzie, Peter Ian
2004Regulation of UDP-glucuronosyltransferases in the gastrointestinal tractGregory, Philip A; Lewinsky, Rikke Holm; Mackenzie, Peter Ian; Gardner-Stephen, Dione Anne
2006Relationship between hyperbilirubinaemia and UDP-glucoronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai patients treated with indinavirBoyd, Mark Alastair; Srasuebkul, Preeyaporn; Ruxrungtham, Kiat; Uchaipichat, Verawan Nu; Mackenzie, Peter Ian; Stek, Michael; Lange, Joep M A; Phanuphak, Praphan; Cooper, David A; Udomuksorn, Wandee; Miners, John Oliver
2006Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) 'probes' for human UDP-glucuronosyltransferasesUchaipichat, Verawan Nu; Mackenzie, Peter Ian; Elliot, David John; Miners, John Oliver
2005S-Naproxen and desmethylnaproxen glucuronidation by human liver miscrosomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxenBowalgaha Ralalage, Kushari Wathsala; Mackenzie, Peter Ian; Knights, Kathleen Mary; Swedmark, S; Miners, John Oliver; Elliot, David John
2006Sulfinpyrazone C-Glucuronidation Is Catalyzed Selectively by Human UDP-Glucuronosyltransferase 1A9Kerdpin, Oranun; Elliot, David John; Mackenzie, Peter Ian; Miners, John Oliver
2004Transciptional Regulation of UDP-GlucuronosyltransferasesXie, W; Mackenzie, Peter Ian; Radominska-Pandya, A
2010UDP-GlucuronosyltransferasesMackenzie, Peter Ian; Gardner-Stephen, Dione Anne;