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Flinders Academic Commons >
Browsing by Author Knights, Kathleen Mary
Showing results 1 to 15 of 15
| Preview | Issue Date | Title | Author(s) | | 2008 | The "albumin effect" and drug
glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance
the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1
and UGT1A6 activities | Mackenzie, Peter Ian; Miners, John Oliver; Knights, Kathleen Mary; Rowland, Andrew |
| 2008 | The "Albumin Effect" and in Vitro-in
Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances
Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450
2C9 | Mackenzie, Peter Ian; Miners, John Oliver; Rowland, Andrew; Elliot, David John; Knights, Kathleen Mary |
| 2007 | Amino acid conjugation: contribution to the
metabolism and toxicity of xenobiotic carboxylic acids | Knights, Kathleen Mary; Sykes, Matthew James; Miners, John Oliver |
| 2007 | Binding of inhibitory fatty acids is responsible
for the enhancement of UDP-Glucuronosyltransferase 2B7 activity by albumin: implications
for in vitro-in vivo extrapolation | Rowland, Andrew; Miners, John Oliver; Gaganis, Paraskevi; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary |
| 2007 | Envenomation and Antivenom | Bryant, Bronwen Jean; Knights, Kathleen Mary |
| 2004 | Evidence that unsaturated fatty acids are potent
inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human
kidney cortical microsomes and recombinant UGT1A9 and UGT2B7 | Tsoutsikos, Paraskevi; Stapleton, Alan Murray; Thomas, Anthony Charles; Knights, Kathleen Mary; Miners, John Oliver; Sallustio, B |
| 2007 | The glucuronidation of delta4-3-keto C19- and
C21-hydroxysteroids by human liver microsomal and recombinant
UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective
substrates for UGT2B7 | Bowalgaha Ralalage, Kushari Wathsala; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary; Miners, John Oliver |
| 2007 | Glucuronidation of fenamates: kinetic studies
using human kidney corticol microsomes and recombinant UDP-glucuronosyltransferase (UGT)
1A9 and 2B7 | Gaganis, Paraskevi; Miners, John Oliver; Knights, Kathleen Mary |
| 2007 | Human renal cortical and medullary
UDP-glucuronosyltransferases (UGTs): immunohistochemical localization of UGT2B7 and
UGT1A enzymes and kinetic characterization of s-naproxen glucuronidation | Thomas, Anthony Charles; Gaganis, Paraskevi; Miners, John Oliver; Brennan, James M; Knights, Kathleen Mary |
| 2008 | In vitro characterisation of human renal and
hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase
enzymes involved in this pathway | Kerdpin, Oranun; Knights, Kathleen Mary; Elliot, David John; Miners, John Oliver |
| 2006 | In vitro-in vivo correlation for drugs and other
compounds eliminated by glucuronidation in humans: Pitfalls and promises | Miners, John Oliver; Knights, Kathleen Mary; Houston, J Brian; Mackenzie, Peter Ian |
| 2007 | In vitro-in vivo extrapolation of drug
glucuronidation kinetic parameters: Pitfalls and Promises | Miners, John Oliver; Rowland, Andrew; Uchaipichat, Verawan Nu; Elliot, David John; Knights, Kathleen Mary; Galetin, A; Houston, J Brian; Mackenzie, Peter Ian |
| 2006 | Non-selective nonsteroidal anti-inflammatory drugs
and cardiovascular events: is aldosterone the silent partner in crime? | Knights, Kathleen Mary; Mangoni, Arduino Aleksander; Miners, John Oliver |
| 2005 | Novel mechanisms of nonsteroidal anti-inflammatory
drug-induced renal toxicity | Knights, Kathleen Mary; Miners, John Oliver; Tsoutsikos, Voula |
| 2005 | S-Naproxen and desmethylnaproxen glucuronidation
by human liver miscrosomes and recombinant human UDP-glucuronosyltransferases (UGT):
role of UGT2B7 in the elimination of naproxen | Bowalgaha Ralalage, Kushari Wathsala; Mackenzie, Peter Ian; Knights, Kathleen Mary; Swedmark, S; Miners, John Oliver; Elliot, David John |
Showing results 1 to 15 of 15
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