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Flinders Academic Commons >
Browsing by Author Miners, John Oliver
Showing results 1 to 20 of 57
| Preview | Issue Date | Title | Author(s) | | 2008 | The "albumin effect" and drug
glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance
the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1
and UGT1A6 activities | Mackenzie, Peter Ian; Miners, John Oliver; Knights, Kathleen Mary; Rowland, Andrew |
| 2008 | The "Albumin Effect" and in Vitro-in
Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances
Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450
2C9 | Mackenzie, Peter Ian; Miners, John Oliver; Rowland, Andrew; Elliot, David John; Knights, Kathleen Mary |
| 2007 | Amino acid conjugation: contribution to the
metabolism and toxicity of xenobiotic carboxylic acids | Knights, Kathleen Mary; Sykes, Matthew James; Miners, John Oliver |
| 2007 | Amino terminal domains of human
UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity
and autoactivation | Lewis, Benjamin Cavell; Mackenzie, Peter Ian; Elliot, David John; Burchell, Brian; Bhasker, Ramana; Miners, John Oliver |
| 2007 | Binding of inhibitory fatty acids is responsible
for the enhancement of UDP-Glucuronosyltransferase 2B7 activity by albumin: implications
for in vitro-in vivo extrapolation | Rowland, Andrew; Miners, John Oliver; Gaganis, Paraskevi; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary |
| 2007 | Carboxylic Acid Drug-Induced DNA Nicking in HEK293
Cells Expressing Human UDP-Glucuronosyltransferases: Role of Acyl Glucuronide
Metabolites and Glycation Pathways | Mackenzie, Peter Ian; DeGraaf, Yvette; Southwood, H; Burcham, P; Miners, John Oliver; Sallustio, B |
| 2007 | Characterisation of the Binding of Cationic
Amphiphilic Drugs to Phospholipid Bilayers using Surface Plasmon Resonance | Shapter, Joseph George; Sykes, Matthew James; Miners, John Oliver; Nussio, Matthew Robert |
| 2006 | Characterization of chloropromazine binding to
lipid bilayer membranes | Nussio, Matthew Robert; Sykes, Matthew James; Shapter, Joseph George; Miners, John Oliver |
| 2007 | Comparative homology modeling of human cytochrome
P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin
O-deethylation by site-directed mutagenesis and enzyme kinetic analysis | Miners, John Oliver; Lewis, Benjamin Cavell; Mackenzie, Peter Ian |
| 2003 | Comparison of linear and nonlinear classification
algorithms for the prediction of drug and chemical metabolism by human
UDP-glucuronosyltransferase isoforms. | Winkler, D A; Smith, Paul Alexander; Miners, John Oliver; Burden, F R; McKinnon, Ross A; Sorich, Michael J |
| 2008 | The configuration of the 17-hydroxy group variably
influences the glucuronidation of B-estradiol and epiestradiol by human
UDP-Glucuronosyltransferases | Itaaho, Katrina; Mackenzie, Peter Ian; Ikushiro, Shin-ichi; Miners, John Oliver; Finel, Moshe |
| 2007 | Critical roles of residues 36 and 40 in the phenol
and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3
and 1A4 | Kubota, Takahiro; Mackenzie, Peter Ian; Miners, John Oliver; Lewis, Benjamin Cavell; Elliot, David John |
| 2004 | Differential contribution of active site residues
in substrate recognition sites 1 and 5 to cytochrome P450 2C8 substrate selectivity and
regioselectivity | Yoovathaworn, Krontong; Kerdpin, Oranun; Miners, John Oliver; Boye, S; Birkett, Donald John; Elliot, David John |
| 2005 | Electrochemical characterisation of the human
cytochrome P450 CYP2C9 | Lewis, Benjamin Cavell; Johnson, D L; Miners, John Oliver; Martin, L L; Elliot, David John |
| 2006 | An evaluation of potential mechanism-based
inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase
inhibitors, including isoniazid | Polasek, Thomas Metodey; Elliot, David John; Somogyi, Andrew A; Gillam, Elizabeth M J; Lewis, Benjamin Cavell; Miners, John Oliver |
| 2004 | Evidence that unsaturated fatty acids are potent
inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human
kidney cortical microsomes and recombinant UGT1A9 and UGT2B7 | Tsoutsikos, Paraskevi; Stapleton, Alan Murray; Thomas, Anthony Charles; Knights, Kathleen Mary; Miners, John Oliver; Sallustio, B |
| 2007 | The glucuronidation of delta4-3-keto C19- and
C21-hydroxysteroids by human liver microsomal and recombinant
UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective
substrates for UGT2B7 | Bowalgaha Ralalage, Kushari Wathsala; Elliot, David John; Mackenzie, Peter Ian; Knights, Kathleen Mary; Miners, John Oliver |
| 2007 | Glucuronidation of fenamates: kinetic studies
using human kidney corticol microsomes and recombinant UDP-glucuronosyltransferase (UGT)
1A9 and 2B7 | Gaganis, Paraskevi; Miners, John Oliver; Knights, Kathleen Mary |
| 2008 | High resolution chemical mapping of biomimetic
membranes by force volume imaging | Sykes, Matthew James; Flavel, Benjamin Scott; Miners, John Oliver; Shapter, Joseph George; Nussio, Matthew Robert; Voelcker, Nicolas Hans |
| 2007 | Human renal cortical and medullary
UDP-glucuronosyltransferases (UGTs): immunohistochemical localization of UGT2B7 and
UGT1A enzymes and kinetic characterization of s-naproxen glucuronidation | Thomas, Anthony Charles; Gaganis, Paraskevi; Miners, John Oliver; Brennan, James M; Knights, Kathleen Mary |
Showing results 1 to 20 of 57
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