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Please use this identifier to cite or link to this item: http://hdl.handle.net/2328/26226

Title: Obstructive sleep apnea and depression
Authors: Harris, Melanie
Glozier, Nick
Ratnavadivel, Rajeev
Grunstein, R R
Keywords: Health
Depression
Sleep disorders
Issue Date: 2009
Publisher: Elsevier
Citation: Harris, M., Glozier, N., Ratnavadivel, R. & Grunstein, R. R., 2009. Obstructive sleep apnea and depression. Sleep Medicine Reviews, 13(6), 437-444.
Abstract: There are high rates of depression in people with obstructive sleep apnea (OSA) in both community and clinical populations. A large community study reported a rate of 17% and reports for sleep clinic samples range between 21% and 41%. A large cohort study found OSA to be a risk factor for depression, but we are unaware of any longitudinal study of the reverse association. However correlations have not generally been found in smaller studies. Several possible causal mechanisms linking OSA and depression have been proposed but not established. Patients who have depression as well as OSA appear worse off than those with OSA only, and depressive symptoms persist in at least some patients in short term studies of treatment for OSA. Direct treatment of depression in OSA might improve acceptance of therapy, reduce sleepiness and fatigue and improve quality of life, but intervention trials are required to answer this question.
URI: http://hdl.handle.net/2328/26226
ISSN: 1087-0792
Appears in Collections:Flinders Human Behaviour and Health Research Unit - Collected Works

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