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Please use this identifier to cite or link to this item: http://hdl.handle.net/2328/3175

Title: Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project
Authors: Laatikainen, Tiina K M
Dunbar, James Anthony
Chapman, Anna Kristina
Kilkkinen, Annamari
Vartiainen, Erkki
Heistaro, Sami Mikael
Philpot, Benjamin Joel
Absetz, Pilvikki
Bunker, Stephen
O'Neil, Adrienne Elizabeth
Reddy, Prasuna
Best, James D
Janus, Edward Denis
Keywords: *Diabetes Mellitus, Type 2 -- Prevention & Control
Health Promotion -- Methods
Rural Health Services
Issue Date: 19-Sep-2007
Publisher: BioMed Central - http://www.biomedcentral.com
Citation: Laatikainen T, Dunbar JA, Chapman A, Kilkkinen A, Vartiainen E, Heistaro S, Philpot B, Absetz P, Bunker S, O'Neil A E, Reddy P, Best JD, Janus ED 2007 Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project. BMC Public Health 2007, 7:249
Abstract: Background Randomised controlled trials demonstrate a 60% reduction in type 2 diabetes incidence through lifestyle modification programmes. The aim of this study is to determine whether such programmes are feasible in primary health care. Methods An intervention study including 237 individuals 40–75 years of age with moderate or high risk of developing type 2 diabetes. A structured group programme with six 90 minute sessions delivered during an eight month period by trained nurses in Australian primary health care in 2004–2006. Main outcome measures taken at baseline, three, and 12 months included weight, height, waist circumference, fasting plasma glucose and lipids, plasma glucose two hours after oral glucose challenge, blood pressure, measures of psychological distress and general health outcomes. To test differences between baseline and follow-up, paired t-tests and Wilcoxon rank sum tests were performed. Results At twelve months participants' mean weight reduced by 2.52 kg (95% confidence interval 1.85 to 3.19) and waist circumference by 4.17 cm (3.48 to 4.87). Mean fasting glucose reduced by 0.14 mmol/l (0.07 to 0.20), plasma glucose two hours after oral glucose challenge by 0.58 mmol/l (0.36 to 0.79), total cholesterol by 0.29 mmol/l (0.18 to 0.40), low density lipoprotein cholesterol by 0.25 mmol/l (0.16 to 0.34), triglycerides by 0.15 mmol/l (0.05 to 0.24) and diastolic blood pressure by 2.14 mmHg (0.94 to 3.33). Significant improvements were also found in most psychological measures. Conclusion This study provides evidence that a type 2 diabetes prevention programme using lifestyle intervention is feasible in primary health care settings, with reductions in risk factors approaching those observed in clinical trials.
Description: Trial Number Current Controlled Trials ISRCTN38031372
URI: http://hdl.handle.net/2328/3175
ISSN: 1471-2458
Appears in Collections:James Dunbar
Prasuna Reddy

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