|
Flinders Academic Commons >
Research Publications >
06 - Biological Sciences and Biotechnology >
0605 - Microbiology >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2328/9304
|
| Title: | Transmembrane Helix 12 of the Staphylococcus
aureus Multidrug Transporter QacA Lines the Bivalent Cationic Drug Binding
Pocket |
| Authors: | Skurray, Ronald Anthony
Hassan, Karl Adam
Brown, Melissa Hackett |
| Issue Date: | 2007 |
| Citation: | Hassan, K.A., Skurray, R.A., & Brown,
M.H., 2007. Transmembrane Helix 12 of the Staphylococcus aureus Multidrug Transporter
QacA Lines the Bivalent Cationic Drug Binding Pocket. Journal of Bacteriology, 189(24),
9131-9134. |
| Abstract: | An acidic residue in transmembrane segment (TMS) 10 is important for recognition of bivalent cationic
substrates by the QacA multidrug transporter. Remarkably, an acidic residue in TMS 12 compensated for the
absence of such a residue in TMS 10, suggesting that TMS 12 is a component of the bivalent cation-binding
region. |
| URI: | http://hdl.handle.net/2328/9304 |
| ISSN: | 0021-9193 |
| Appears in Collections: | 0605 - Microbiology
|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
|
