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Please use this identifier to cite or link to this item: http://hdl.handle.net/2328/9304

Title: Transmembrane Helix 12 of the Staphylococcus aureus Multidrug Transporter QacA Lines the Bivalent Cationic Drug Binding Pocket
Authors: Skurray, Ronald Anthony
Hassan, Karl Adam
Brown, Melissa Hackett
Issue Date: 2007
Citation: Hassan, K.A., Skurray, R.A., & Brown, M.H., 2007. Transmembrane Helix 12 of the Staphylococcus aureus Multidrug Transporter QacA Lines the Bivalent Cationic Drug Binding Pocket. Journal of Bacteriology, 189(24), 9131-9134.
Abstract: An acidic residue in transmembrane segment (TMS) 10 is important for recognition of bivalent cationic substrates by the QacA multidrug transporter. Remarkably, an acidic residue in TMS 12 compensated for the absence of such a residue in TMS 10, suggesting that TMS 12 is a component of the bivalent cation-binding region.
URI: http://hdl.handle.net/2328/9304
ISSN: 0021-9193
Appears in Collections:0605 - Microbiology

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