College of Medicine and Public Health
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The College of Medicine and Public Health deliver clinical, population and lab based research, integrated teaching programs and high quality clinical services.
Our teaching footprint reaches out from our world class teaching hospital at the Flinders Medical Centre in South Australia to multiple rural clinical locations all the way to Darwin in the Northern Territory.
We promote research in health services, systems improvements, public and population health, improved clinical care and laboratory and precision medicine.
This approach has seen us investigate everything from community health problems to the smallest of molecules that influence human disease.
Our research and teaching equips the next generation of leaders and innovators with the skill, commitment and vision to protect vulnerable communities and truly advance health outcomes. It’s at the heart of everything we do.
It’s about improving the health and wellbeing for everyone in society.
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Recent Submissions
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Neuropsychiatric aspects of frontal lobe meningioma
(Elsevier, 2017-07-14)Brain tumours are known to typically present with neurological signs. Rarely, psychiatric symptoms can be the only manifestation of a brain tumour (Madhusoodanan et al., 2015). Though it is not uncommon for patients to ... -
Outcomes of Older Patients (≥ 70 Years) Treated With Targeted Therapy in Metastatic Chemorefractory Colorectal Cancer: Retrospective Analysis of NCIC CTG CO.17 and CO.20
(Elsevier, 2018-11-28)Background The safety and efficacy of targeted therapy in older patients (≥ 70 years) with metastatic colorectal cancer is not well evaluated. Patients and Methods Outcomes of older patients (including overall ... -
Effect of Flammulina velutipes on the physicochemical and sensory characteristics of Cantonese sausages
(Elsevier, 2019-04-03)The effects of fresh and dried Flammulina velutipes (FFV and DFV) on quality and sensory characteristics of Cantonese sausages were investigated. Sausage samples were prepared by adding 0% (control), 2.5% FFV, 2.5% and ... -
Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy
(Elsevier, 2019-04-09)A major challenge in broader clinical application of Jack Jumper ant venom immunotherapy (JJA VIT) is the scarcity of ant venom which needs to be manually harvested from wild ants. Adjuvants are commonly used for antigen ... -
Use of illicit amphetamines is associated with long-lasting changes in hand circuitry and control
(Elsevier, 2019-02-26)Objective The study aim was to determine if use of illicit amphetamines or ecstasy is associated with abnormal excitability of the corticomotoneuronal pathway and manipulation of novel objects with the hand. Methods Three ... -
Micromanaging aerobic respiration and glycolysis in cancer cells
(Elsevier, 2019-02-06)Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic circuits, to support the energetic and ... -
Phytol: A review of biomedical activities
(Elsevier, 2018-04-18)Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil ... -
Case report: Identification of intra-laboratory blood culture contamination with Staphylococcus aureus by whole genome sequencing
(Elsevier, 2019-02-23)Staphylococcus aureus in blood cultures is rarely considered a contaminant. We report a case of intra-laboratory contamination between blood culture bottles which was confirmed by whole genome sequencing, highlighting the ... -
A Roberts Syndrome Individual With Differential Genotoxin Sensitivity and a DNA Damage Response Defect
(Elsevier, 2018-11-30)Purpose Roberts syndrome (RBS) is a rare, recessively transmitted developmental disorder characterized by growth retardation, craniofacial abnormalities, and truncation of limbs. All affected individuals to date have ... -
Bilateral diffuse pulmonary infiltrates secondary to malignant peritoneal mesothelioma – A rare clinical presentation
(Elsevier, 2019-03-04)Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure ... -
Interventions targeting the prescribing and monitoring of vancomycin for hospitalized patients: a systematic review with meta-analysis
(Dove Press, 2018-10-31)Purpose: Vancomycin prescribing requires individualized dosing and monitoring to ensure efficacy, limit toxicity, and minimize resistance. Although there are nationally endorsed guidelines from several countries addressing ... -
A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis
(Springer Nature Publishing AG, 2018-06-01)Recent advances in high-throughput technologies have provided an unprecedented opportunity to identify molecular markers of disease processes. This plethora of complex-omics data has simultaneously complicated the problem ... -
Sustained improvement in vancomycin dosing and monitoring post-implementation of guidelines: Results of a three-year follow-up after a multifaceted intervention in an Australian teaching hospital
(Elsevier, 2018-02)Introduction Despite vancomycin being in use for over half-a-century, it is still not dosed or monitored appropriately in many centers around the world. The objective of this study was to determine the effectiveness of ... -
Adherence to antibiotic guidelines and reported penicillin allergy: pooled cohort data on prescribing and allergy documentation from two English National Health Service (NHS) trusts
(BMJ Publishing group, 2019-03-01)Objective To investigate documentation of antimicrobial allergy and to determine prescribing adherence to local antibiotic guidelines for inpatients with and without reported penicillin allergy treated for infection in a ... -
Burkholderia lata Infections from Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016
(Centers for Disease Control and Prevention, 2018-11)Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated ... -
Monte Carlo Simulations Demonstrate Algorithmic Interventions Over Time Reduce Hospitalisation in Patients With Schizophrenia and Bipolar Disorder
(Sage Journals, 2018-10-02)Non-adherence with pharmacologic treatment is associated with increased rates of relapse and rehospitalisation among patients with schizophrenia and bipolar disorder. To improve treatment response, remission, and recovery, ... -
C-Reactive Protein: Higher During Acute Psychotic Episodes and Related to Cortical Thickness in Schizophrenia and Healthy Controls
(Frontiers, 2018-10-10)There is increasing evidence for the role of inflammation in schizophrenia, yet the stability of increased peripheral inflammation in acute psychosis and the degree to which peripheral inflammation relates to cortical ... -
Mechanisms Underlying Overactive Bladder and Interstitial Cystitis/Painful Bladder Syndrome
(Frontiers, 2018-12-12)The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal cord, providing sensory input to the micturition centers within the central nervous system. Under normal conditions, the ... -
Immunological failure in HIV-infected adults from 2003 to 2015 in Southwest Ethiopia: a retrospective cohort study
(BMJ Publishing group, 2018-07-10)Objective To assess the prevalence, trend and associated factors for immunological failure (IF), and the magnitude of antiretroviral therapy (ART) shift among adults infected with HIV in Southwest Ethiopia. Setting A ... -
Risk Factors for Severe Diarrhea with an Afatinib Treatment of Non-Small Cell Lung Cancer: A Pooled Analysis of Clinical Trials
(MDPI, 2018-10-15)Afatinib is an effective therapy for metastatic non-small cell lung cancer (NSCLC) but it is associated with a relatively high incidence of severe diarrhea. The association between pre-treatment candidate predictors (age, ...
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