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dc.contributor.authorSmith, Eric
dc.contributor.authorJones, Michael Emlyn
dc.contributor.authorDrew, Paul Anthony
dc.date.accessioned2012-10-02T03:14:56Z
dc.date.available2012-10-02T03:14:56Z
dc.date.issued2009
dc.identifier.citationSmith, E., Jones, M.E., & Drew, P.A., 2009. Quantitation of DNA methylation by melt curve analysis. BMC Cancer, 9:123 (24 April 2009).en
dc.identifier.issn1471-2407
dc.identifier.urihttp://hdl.handle.net/2328/26328
dc.description.abstractWe have validated a rapid, simple in-tube method to quantify methylation which is robust and reproducible, utilizes easily designed primers and does not need proprietary algorithms or software. The technique does not depend on any operator manipulation or interpretation of the melt curves, and is suitable for use in any laboratory with a real-time thermocycler. The parameters derived provide an objective description and quantitation of the methylation in a specimen, and can be used for statistical comparisons of methylation between specimens.en
dc.language.isoen
dc.publisherBioMed Central Ltd.en
dc.subjectMedicineen
dc.subjectPublic healthen
dc.subjectCanceren
dc.subjectDNA methylationen
dc.titleQuantitation of DNA methylation by melt curve analysisen
dc.typeArticleen
dc.identifier.rmid2006013533
dc.identifier.doihttps://doi.org/10.1186/1471-2407-9-123en
local.contributor.authorOrcidLookupDrew, Paul Anthony: https://orcid.org/0000-0001-5661-4771en_US


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