Now showing items 1-2 of 2

    • Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis 

      Nones, Katia; Waddell, Nicola; Wayte, Nicci; Patch, Ann-Marie; Bailey, Peter; Newell, Felicity; Holmes, Oliver; Fink, J. Lynn; Quinn, Michael C.J.; Tang, Yue Hang; Lampe, Guy; Quek, Kelly; Loffler, Kelly A; Manning, Suzanne; Idrisoglu, Senel; Miller, David; Xu, Qinying; Waddell, Nick; Wilson, Peter J; Bruxner, Timothy J C; Christ, Angelika N; Harliwong, Ivon; Nourse, Craig; Nourbakhsh, Ehsan; Anderson, Matthew F; Kazakoff, Stephen H; Leonard, Conrad; Wood, Scott; Simpson, Peter; Reid, Lynne E; Krause, Lutz; Hussey, Damian James; Watson, David Ian; Lord, Reginald V; Nancarrow, Derek J; Phillips, Wayne A; Gotley, David C; Smithers, B Mark; Whiteman, David C; Hayward, Nicholas K; Campbell, Peter J; Pearson, John V; Grimmond, Sean M; Barbour, Andrew P (Nature Publishing Group, 2014)
      Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes. While large EAC exome sequencing ...
    • Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma 

      Krause, Lutz; Nones, Katia; Loffler, Kelly A; Nancarrow, Derek J; Oey, Harald; Tang, Yue Hang; Wayte, Nicci; Patch, Ann-Marie; Patel, Kalpana; Thomas, Janine; Stoye, Jens; Hussey, Damian James; Watson, David Ian; Lord, Reginald V; Phillips, Wayne A; Gotley, David C; Smithers, B Mark; Whiteman, David C; Hayward, Nicholas K; Grimmond, Sean M; Waddell, Nicola; Barbour, Andrew P (Oxford University Press, 2016)
      The incidence of esophageal adenocarcinoma (EAC) has risen significantly over recent decades. Although survival has improved, cure rates remain poor, with <20% of patients surviving 5 years. This is the first study to ...