Now showing items 81-100 of 174

    • The Impact of Diabetic Retinopathy and Diabetic Macular Edema on Health-Related Quality of Life in Type 1 and Type 2 Diabetes 

      Fenwick, E K; Xie, J; Ratcliffe, Julia; Pesudovs, Konrad; Finger, R P; Wong, T Y; Lamoureux, E L (Association for Research in Vision and Ophthalmology, Inc., 2012-02)
      Purpose.: To assess the impact of diabetic retinopathy (DR) and diabetic macular edema (DME) on health-related quality of life (HRQoL) in type 1 and type 2 diabetes using the EuroQoL EQ-5D generic multi-attribute utility ...
    • The Impact of Structural and Functional Parameters in Glaucoma Patients on Patient-Reported Visual Functioning 

      Hirnei, C; Reznicek, L; Vogel, M; Pesudovs, Konrad (Public Library of Science, 2013-12-03)
    • The Importance of Rating Scale Design in the Measurement of Patient-Reported Outcomes Using Questionnaires or Item Banks 

      Khadka, Jyoti; McAlinden, Colm; Gothwal, V K; Lamoureux, E L; Pesudovs, Konrad (Association for Research in Vision and Ophthalmology, Inc., 2012-06)
      Purpose.: To investigate the effect of rating scale designs (question formats and response categories) on item difficulty calibrations and assess the impact that rating scale differences have on overall vision-related ...
    • In vitro adenovirus mediated gene transfer to the human cornea 

      Jessup, Claire Frances; Brereton, Helen Mary; Coster, Douglas John; Williams, Keryn Anne (BMJ Publishing Group -, 2005-06)
      BACKGROUND/AIMS: Replication deficient adenovirus is an efficient vector for gene transfer to the cornea. The aim was to optimise the transduction of human corneal endothelium with adenoviral vectors and to measure transgene ...
    • Influence of advanced recipient and donor age on the outcome of corneal transplantation. Australian Corneal Graft Registry. 

      Williams, Keryn Anne; Muehlberg, S M; Lewis, R F; Coster, Douglas John (BMJ Publishing Group -, 1997-10)
      AIMS: The aims of this study were to examine the influence of advanced recipient and donor age on the long term outcome of corneal transplantation. METHODS: Records of 1036 penetrating corneal grafts in recipients aged > ...
    • The influence of Australian eye banking practices on corneal graft survival 

      Keane, Miriam Claire; Lowe, Marie T; Coster, Douglas John; Pollock, Graeme A; Williams, Keryn Anne (Australasian Medical Publishing Company, 2013-08-19)
      Donor corneas transported interstate exhibited poorer survival after transplantation than those retrieved and grafted locally. Higher proportions of emergency procedures involving transported corneas did not account for ...
    • Influence of format on in vitro penetration of antibody fragments through porcine cornea 

      Brereton, Helen Mary; Taylor, Susan D; Farrall, Alexandra L; Hocking, Dianna M; Thiel, Michael A; Tea, Melinda Nay; Coster, Douglas John; Williams, Keryn Anne (BMJ Publishing Group -, 2005-09)
      AIM: Antibody fragments, appropriately formulated, can penetrate through the ocular surface and thus have potential as therapeutic agents. The aim was to investigate the influence of protein fragment format on the kinetics ...
    • The Influence of Rejection Episodes in Recipients of Bilateral Corneal Grafts 

      Williams, Keryn Anne; Kelly, T L; Lowe, Marie Therese; Coster, Douglas John (2010)
      We investigated whether a rejection episode in one graft was associated with rejection in the other graft, in recipients with bilateral corneal transplants. In a prospectively maintained, national register of 14 ...
    • Influence of the time of day on axial length and choroidal thickness changes to hyperopic and myopic defocus in human eyes 

      Moderiano, Daniel; Do, Michelle; Hobbs, Sam; Lam, Vy; Sarin, Simran; Alonso-Caneiro, David A; Chakraborty, Ranjay (Elsevier, 2019-03-26)
      Research in animal models have shown that exposing the eye to positive or negative spectacle lenses can lead to predictable changes in eye growth. Recent research indicates that brief periods (1–2 h) of monocular defocus ...
    • Intercellular adhesion molecule 1 mediates migration of Th1 and Th17 cells across human retinal vascular endothelium 

      Bharadwaj, A S; Schewitz-Bowers, L P; Wei, L; Lee, R W; Smith, Justine R (Association for Research in Vision and Ophthalmology, 2013)
      Purpose. Autoimmune inflammation of the retina causes vision loss in the majority of affected individuals. Th1 or Th17 cells initiate the disease on trafficking from the circulation into the eye across the retinal vascular ...
    • Intracameral antibiotics for prophylaxis of post operative endophthalmitis in Australia : comment 

      Phillips, Cameron J; Mills, Richard Arthur (Wiley, 2019-10-01)
      We read with interest the article by Lipsky and Barrett and concur that intracameral moxifloxacin is a safer and more efficacy alternative to vancomycin as evidence emerges of postoperative haemorrhagic ...
    • Investigation of crystallin genes in familial cataract, and report of two disease associated mutations. 

      Burdon, Kathryn Penelope; Wirth, M Gabriela; Mackey, David A; Russell-Eggit, Isabelle M; Craig, Jamie E; Elder, James E; Dickinson, Joanne L; Sale, Michele M (BMJ Publishing Group -, 2004-01)
      AIMS: Mutations of seven crystallin genes have been shown to cause familial cataract. The authors aimed to identify disease causing crystallin mutations in paediatric cataract families from south eastern Australia. METHODS: ...
    • Investigation of eight candidate genes on chromosome 1p36 for autosomal dominant total congenital cataract 

      Mackey, David A; Craig, Jamie E; Burdon, Kathryn Penelope; Lachke, Salil A; Hattersely, Kathryn; Laurie, Kate; Maas, Richard L (2008)
    • The influence of cervical and thoracic lymphadenectomy on corneal allograft rejection in inbred rats 

      Brice, Sarah L; Kirk, Kirsty; Brereton, Helen Mary; Coster, Douglas John; Williams, Keryn Anne (BMJ Group, 2011-11-23)
      Aim To investigate the site of alloantigen presentation in the rat following orthotopic corneal transplantation. Methods Adult inbred Fischer 344 rats received penetrating corneal allografts from inbred Wistar Furth donors ...
    • Lack of cone mediated retinal function increases susceptibility to form-deprivation myopia in mice 

      Chakraborty, Ranjay; Yang, Victoria; Park, Han Na; Landis, Erica G; Dhakal, Susov; Motz, Cara T; Bergen, Michael A; Iuvone, P Michael; Pardue, Machelle T (Elsevier, 2018-12-31)
      Retinal photoreceptors are important in visual signaling for normal eye growth in animals. We used Gnat2cplf3/cplf3 (Gnat2−/−) mice, a genetic mouse model of cone dysfunction to investigate the influence of cone signaling ...
    • A large genome-wide association study of age-related macular degeneration highlights contribution of rare and common variants 

      Fritsche, Lars G; Igl, Wilmar; Cooke-Bailey, Jessica N; Grassmann, Felix; Sengupta, Sebanti; Bragg-Gresham, Jennifer L; Burdon, Kathryn Penelope; Hebbring, Scott J; Wen, Cindy; Gorski, Mathias; Kim, Ivana K; Cho, David; Zack, Donald; Souied, Eric; Scholl, Hendrik P N; Bala, Elisa; Lee, Kristine E; Hunter, David J; Sardell, Rebecca J; Mitchell, Paul; Merriam, Joanna E; Cipriani, Valentina; Hoffman, Joshua D; Schick, Tina; Lechanteur, Yara T E; Guymer, Robyn H; Johnson, Matthew P; Jiang, Yingda; Stanton, Chloe M; Buitendijk, Gabrielle H S; Zhan, Xiaowei; Kwong, Alan M; Boleda, Alexis; Brooks, Matthew; Gieser,Linn; Ratnapriya, Rinki; Branham, Kari E; Foerster, Johanna R; Heckenlively, John R; Othman, Mohammad I; Vote, Brendan J; Liang, Helena Hai; Souzeau, Emmanuelle; McAllister, Ian L; Isaacs, Timothy; Hall, Janette; Lake, Stewart; Mackey, David A; Constable, Ian J; Craig, Jamie E; Kitchner, Terrie E; Yang, Zhenglin; Su, Zhiguang; Luo, Hongrong; Chen, Daniel; Ouyang, Hong; Flegg, Ken; Lin, Danni; Mao, Guanping; Ferreyra, Henry; Stark, Klaus; von Strachwitz, Claudia N; Wolf, Armin; Brandl, Caroline; Rudolph, Guenther; Olden, Matthias; Morrison, Margaux A; Morgan, Denise J; Schu, Matthew; Ahn, Matthew; Silvestri, Giuliana; Tsironi, Evangelia E; Park, Kyu Hyung; Farrer, Lindsay A; Orlin, Anton; Brucker, Alexander; Li, Mingyao; Curcio, Christine; Mohand-Saïd, Saddek; Sahel, Jose-Alain; Audo, Isabelle; Benchaboune, Mustapha; Cree, Angela J; Rennie, Christina A; Goverdhan, Srinivas V; Grunin, Michelle; Hagbi-Levi, Shira; Campochiaro, Peter; Katsanis, Nicholas; Holz, Frank G; Blond, Frederic; Blanche, Helene; Deleuze, Jean-Francois; Igo Jr, Robert P; Truitt, Barbara; Peachey, Neal S; Meuer, Stacy M; Myers, Chelsea E; Moore, Emily M; Klein, Ronald; Hauser, Michael A; Postel, Eric A; Courtenay, Monique D; Schwartz, Stephen G; Kovach, Jaclyn L; Scott, William K; Liew, Gerald; Tan, Ava G; Gopinath, Bamini; Merriam, John C; Smith, R Theodore; Khan, Jane C; Shahid, Humma; Moore, Anthony T; McGrath, J Allie; Laux, Rene; Brantley Jr., Milam A; Agarwal, Anita; Ersoy, Lebriz; Caramoy, Albert; Langmann, Thomas; Saksens, Nicole T M; de Jong, Eiko K; Hoyng, Carel B; Cain, Melinda S; Richardson, Andrea J; Martin,Tammy M; Blangero, John; Weeks, Daniel E; Dhillon, Bal; van Duijn, Cornelia M; Doheny, Kimberly F; Romm, Jane; Klaver, Caroline C W; Hayward, Caroline; Gorin, Michael B; Klein, Michael L; Baird, Paul N; den Hollander, Anneke I; Fauser, Sascha; Yates, John R W; Allikmets, Rando; Wang, Jie Jin; Schaumberg, Debra A; Klein, Barbara E K; Hagstrom, Stephanie A; Chowers, Itay; Lotery, Andrew J; Léveillard, Thierry; Zhang, Kang; Brilliant, Murray H; Hewitt, Alex W; Swaroop, Anand; Chew, Emily Y; Pericak-Vance, Margaret A; DeAngelis, Margaret; Stambolian, Dwight; Haines, Jonathan L; Iyengar, Sudha K; Weber, Bernhard H F; Abecasis, Goncalo R (Nature Publishing Group, 2015-12-21)
      Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the elderly, with limited therapeutic options. Here we report on a study of >12 million variants, including 163,714 directly genotyped, ...
    • Late onset post-keratoplasty astigmatism in patients with keratoconus 

      Lim, L; Pesudovs, Konrad; Goggin, M; Coster, Douglas John (BMJ Publishing Group -, 2004-03)
      AIM: 10 eyes of 10 patients are reported where progression of keratoconus in the host cornea occurred more than 10 years after penetrating keratoplasty with resultant increase in astigmatism. The technique and results of ...
    • Letter to the Editor: Simultaneous presentation of hereditary hyperferritinaemia cataract syndrome and hereditary haemochromatosis 

      Maccora, Katia A; Souzeau, Emmanuelle; Ruddle, Jonathan B; Craig, Jamie E (Wiley, 2018-05-08)
      "No abstract is available for this article"- Publisher
    • Letter: Pervasive Blindness and ocular morbidity in the Chepang people of Nepal 

      Kandel, Amrit; Kandel, Himal; Shrestha, Priyanka (Nepal Ophthalmic Society, 2016)
    • Loss of ciliary zonule protein hydroxylation and lens stability as a predicted consequence of biallelic ASPH variation 

      Siggs, Owen M; Souzeau, Emmanuelle; Craig, Jamie E (Taylor & Francis Group, 2019-01-02)
      Purpose: Stability of the crystalline lens requires formation of microfibril bundles and their higher-order structures of ciliary zonules. Trauma, malformation, or degeneration of the ciliary zonules can lead to dislocation ...