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Recent Submissions

  • Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma 

    Gharahkhani, Puya; Burdon, Kathryn Penelope; Cooke-Bailey, Jessica N; Hewitt, Alex W; Law, Matthew H; Pasquale, Louis R; Kang, Jae Hee; Haines, Jonathan L; Souzeau, Emmanuelle; Zhou, Tiger; Siggs, Owen M; Landers, John; Awadalla, Mona S; Sharma, Shiwani; Mills, Richard Arthur; Ridge, Bronwyn; Lynn, David J; Casson, Robert J; Graham, Stuart L; Goldberg, Ivan; White, Andrew J; Healey, Paul R; Grigg, John RB; Lawlor, Mitchell; Mitchell, Paul; Ruddle, Jonathan B; Coote, Michael A; Walland, Mark; Best, Stephen; Vincent, Andrea; Gale, Jesse; Radford-Smith, Graham; Whiteman, David C; Montgomery, Grant W; Martin, Nicholas G; Mackey, David A; Wiggs, Janey L; MacGregor, Stuart; Craig, Jamie E; Neighborhood Consortium (Nature Publishing Group, 2018-02-18)
    Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further ...
  • DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma 

    Burdon, Kathryn Penelope; Awadalla, Mona S; Mitchell, Paul; Wang, Jie Jin; White, Andrew J; Keane, Miriam Claire; Souzeau, Emmanuelle; Graham, Stuart L; Goldberg, Ivan; Healey, Paul R; Landers, John; Mills, Richard Arthur; Best, Stephen; Hewitt, Alex W; Sharma, Shiwani; Craig, Jamie E (Taylor & Francis Group, 2017-12-21)
    Purpose: Recent genome-wide association studies reported strong association of genetic variation at the CDKN2B/CDKN2B-AS1 locus on 9p21 with normal-tension glaucoma (NTG) in multiple populations. The mechanism by which ...
  • Rare, Potentially Pathogenic Variants in ZNF469 Are Not Enriched in Keratoconus in a Large Australian Cohort of European Descent 

    Lucas, Sionne E; Zhou, Tiger; Blackburn, Nicholas B; Mills, Richard Arthur; Ellis, Jonathan; Leo, Paul; Souzeau, Emmanuelle; Ridge, Bronwyn; Charlesworth, Jac C; Brown, Matthew A; Lindsay, Richard; Craig, Jamie E; Burdon, Kathryn Penelope (Investigative Ophthalmology and Visual Science, 2017-12)
    Purpose: The Zinc Finger Protein 469 (ZNF469) gene has been proposed as a candidate gene for keratoconus due to the association of an upstream polymorphism (rs9938149) with the disease in two independent studies, and the ...
  • Angiopoietin-1 is required for Schlemm’s canal development in mice and humans 

    Thomson, Benjamin R; Souma, Tomokazu; Tompson, Stuart W; Onay, Tuncer; Kizhatil, Krishnakumar; Siggs, Owen M; Feng, Liang; Whisenhunt, Kristina N; Yanovitch, Tammy L; Kalaydjieva, Luba; Azmanov, Dimitar N; Finzi, Simone; Tanna, Christine A; Hewitt, Alex W; Mackey, David A; Bradfield, Yasmin S; Souzeau, Emmanuelle; Javadiyan, Shahrbanou; Wiggs, Janey L; Pasutto, Francesca; Liu, Xiaorong; John, Simon W M; Craig, Jamie E; Jin, Jing; Young, Terri L; Quaggin, Susan (American Society for Clinical Investigation, 2017-11)
    Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures, Schlemm’s canal (SC) and the trabecular meshwork. We ...
  • Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis 

    Flaxman, Seth R; Bourne, Rupert R A; Resnikoff, Serge; Ackland, Peter; Braithwaite, Tasanee; Cicinelli, Maria V; Das, Aditi; Jonas, Jost B; Keeffe, Jill E; Kempen, John H; Leasher, Janet; Limburg, Hans; Naidoo, Kovin; Pesudovs, Konrad; Silvester, Alex; Stevens, Gretchen A; Tahhan, Nina; Wong, Tien Yin; Taylor, Hugh R; Vision Loss Expert Group of the Global Burden of Disease Study (Elsevier, 2017-10-11)
    Background Contemporary data for causes of vision impairment and blindness form an important basis of recommendations in public health policies. Refreshment of the Global Vision Database with recently published data sources ...
  • The Mobility Assessment Course for the Diagnosis of Spatial Neglect: Taking a Step Forward? 

    Grech, Megan; Stuart, Tracey; Williams, Lindy; Chen, Celia Shin Wen; Loetscher, Tobias (Frontiers Media S.A., 2017-10-31)
    Spatial neglect after stroke can be a challenging syndrome to diagnose under standard neuropsychological assessment. There is now sufficient evidence that those affected might demonstrate neglect behavior in everyday ...
  • Ideas, actors and institutions: lessons from South Australian Health in All Policies on what encourages other sectors’ involvement 

    Baum, Fran; Delany, Toni; MacDougall, Colin James; Lawless, Angela Patricia; van Eyk, Helen Clare; Williams, Carmel (BioMed Central, 2017-10-16)
    Background This paper examines the extent to which actors from sectors other than health engaged with the South Australian Health in All Policies (HiAP) initiative, determines why they were prepared to do so and explains ...
  • An integrative review of e-learning in the delivery of self-management support training for health professionals 

    Lawn, Sharon Joy; Zhi, Xiaojuan; Morello, Andrea (BioMed Central, 2017-10-10)
    Background E-learning involves delivery of education through Information and Communication Technology (ITC) using a wide variety of instructional designs, including synchronous and asynchronous formats. It can be as ...
  • Teaching Communication Skills: An Australian Optometry Program’s New Course 

    Brandenburg, Rob; Pesudovs, Konrad (Association of Schools and Colleges of Optometry., 2014-09)
    After a review of the literature, the authors describe the experience of developing and teaching a new communication skills course at Flinders University in South Australia. A follow-up survey indicated that optometry ...
  • The National Eye Survey of Trinidad and Tobago (NESTT): Rationale, Objectives and Methodology 

    Braithwaite, Tasanee; Verlander, Neville Q; Bartholomew, Debra; Bridgemohan, Petra; McNamara, Kevin Peter; Roach, Allana; Sharma, Subash; Singh, Deo; Pesudovs, Konrad; Teelucksingh, Surujpal; Carrington, Christine; Ramsewak, Samuel; Bourne, Rupert R A; NESTT Study Group (Taylor & Francis Group, 2017-01-20)
    Purpose: This paper describes the rationale, study design and procedures of the National Eye Survey of Trinidad and Tobago (NESTT). The main objective of this survey is to obtain prevalence estimates of vision impairment ...
  • Number of People Blind or Visually Impaired by Cataract Worldwide and in World Regions, 1990 to 2010 

    Khairallah, Moncef; Kahloun, Rim; Bourne, Rupert R A; Limburg, Hans; Flaxman, Seth R; Jonas, Jost B; Keeffe, Jill E; Leasher, Janet; Naidoo, Kovin; Pesudovs, Konrad; Price, Holly; White, Richard A; Wong, Tien Yin; Resnikoff, Serge; Taylor, Hugh R; Vision Loss Expert Group (ARVO Journals, 2015-10)
    Purpose: To estimate prevalence and number of people visually impaired or blind due to cataract. Methods: Based on the Global Burden of Diseases Study 2010 and ongoing literature research, we examined how many people ...
  • ACE 2016 Handbook : 45th Australian Conference of Economists 

    Flinders University (Flinders University, 2016-07-11)
    Held at Flinders University 11-13 July 2016
  • Public Infrastructure and Private Sector Productivity, Tasmania 1990-2015 

    Mikhailitchenko, Serguei (Flinders University, 2016-07-11)
    The study utilises the recent advances in development of capital stock data at subnational level for Australian states and applies the series for analysis of the effect of the public infrastructure on the private sector ...
  • TGC repeat expansion in the TCF4 gene increases the risk of Fuchs' endothelial corneal dystrophy in Australian cases 

    Kuot, Abraham; Hewitt, Alex W; Snibson, Grant R; Souzeau, Emmanuelle; Mills, Richard Arthur; Craig, Jamie E; Burdon, Kathryn Penelope; Sharma, Shiwani (Public Library of Science, 2017-08-23)
    Fuchs’ endothelial corneal dystrophy (FECD) is a progressive, vision impairing disease. Common single nucleotide polymorphisms (SNPs) and a trinucleotide repeat polymorphism, thymine-guanine-cytosine (TGC), in the TCF4 ...
  • High throughput genetic screening of 51 paediatric cataract genes identifies causative mutations in inherited paediatric cataract in South Eastern Australia 

    Javadiyan, Shahrbanou; Craig, Jamie E; Souzeau, Emmanuelle; Sharma, Shiwani; Lower, Karen Marie; Mackey, David A; Staffieri, Sandra E; Elder, James E; Taranath, Deepa A; Straga, Tania; Black, Joanna; Pater, John Brian; Casey, Theresa; Hewitt, Alex W; Burdon, Kathryn Penelope (Genetics Society of America., 2017-08-24)
    Paediatric cataract is a leading cause of childhood blindness. This study aimed to determine the genetic cause of paediatric cataract in Australian families by screening known disease associated genes using massively ...
  • Divided we fall: clinicians and academic psychiatrists need to stand together 

    Allison, Stephen; Bastiampillai, Tarun; Battersby, Malcolm Wayne (Sage Journals, 2017-07-12)
    Objective: Psychiatry faces urgent problems requiring united action. These problems affect academic psychiatrists in the universities, and clinicians in publicly funded mental health services. Academic units are isolated ...
  • Managing chronic conditions care across primary care and hospital systems: lessons from an Australian Hospital Avoidance Risk Program using the Flinders Chronic Condition Management Program 

    Lawn, Sharon Joy; Zabeen, Sara; Smith, David; Wilson, Ellen; Miller, Cathie; Battersby, Malcolm Wayne; Masman, Kevin (CSIRO Publishing, 2017-08-24)
    Objective The study aimed to determine the impact of the Flinders Chronic Condition Management Program for chronic condition self-management care planning and how to improve its use with Bendigo Health’s Hospital Admission ...
  • Shared Care Involving Cancer Specialists and Primary Care Providers - What Do Cancer Survivors Want? 

    Lawn, Sharon Joy; Fallon-Ferguson, Julia; Koczwara, Bogda (Wiley, 2017-05-03)
    Background Cancer survivors are living longer, prompting greater focus on managing cancer as a chronic condition. Shared care between primary care providers (PCPs) and cancer specialists, involving explicit partnership ...
  • Exploring the Potential for Family Carers to Support People With Mental Illness to Stop Smoking 

    Lawn, Sharon Joy; Bowman, Jenny; Wye, Paula; Wiggers, John (Taylor & Francis Group, 2016-12-05)
    Cigarette smoking poses significant health burdens for people with mental illness. They die sooner than they should, and smoking is a major contributor to their high rates of morbid chronic physical health conditions and ...
  • Researching the Experience of Caring for a Military Veteran Partner With Posttraumatic Stress Disorder Using Interpretive Phenomenology 

    Waddell, Elaine; Pulvirenti, Mariastella; Lawn, Sharon Joy (Sage Journals, 2017)
    Under the supervision of the coauthors, the lead author undertook doctoral research examining the ‘lived experience’ of caring for an Australian military veteran with post-traumatic stress disorder (PTSD) from the perspective ...

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