Now showing items 1-2 of 2

    • An Anti–VEGF-B Antibody Fragment Induces Regression of Pre-Existing Blood Vessels in the Rat Cornea 

      Irani, Yazad; Scotney, Pierre; Klebe, Sonja; Mortimer, Lauren A; Nash, Andrew; Williams, Keryn Anne (ARVO Journals, 2017-07)
      Purpose: We tested the ability of an antibody fragment with specificity for vascular endothelial growth factor-B (VEGF-B) to regress nascent and established corneal blood vessels in the rat. Methods: A single chain variable ...
    • Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions 

      Irani, Yazad; Scotney, Pierre; Nash, Andrew; Williams, Keryn Anne (Association for Research in Vision and Ophthalmology, 2016)
      PURPOSE: The species cross-reactivity of the monoclonal antibodies infliximab, bevacizumab, and an anti-VEGF-B antibody, 2H10, in humans and rodents was determined. METHODS: The binding of infliximab to human, mouse, and ...