Now showing items 1-6 of 6
How should we conduct and interpret phase III clinical trials in palliative care?
The article by Wildiers et al.1 raises some challenges in terms of ethical approaches to phase III end-of-life studies and their interpretation. Although the authors should be commended for undertaking a large, multisite, ...
Current approaches to diagnosing and managing constipation in advanced cancer and palliative care
(Mary Ann Liebert, Inc., 2010-04-12)
Constipation is common in advanced cancer. Despite this, clinicians' understanding of the underlying changes affecting the colon and the rest of the gastrointestinal tract are limited. Two case histories are used to ...
Anti-cholinergic load, health care utilization, and survival in people with advanced cancer: a pilot study
(Mary Ann Liebert, Inc., 2010-07-02)
Introduction: Anti-cholinergic medications have been associated with increased risks of cognitive impairment, premature mortality and increased risk of hospitalisation. Anti-cholinergic load associated with medication ...
Planning phase III multi-site clinical trials in palliative care: the role of consecutive cohort audits to identify potential participant populations
Goals of Work: Multiple sites enable more successful completion of adequately powered phase III studies in palliative care. Audits of the frequency and distribution of the symptoms of interest can better inform research ...
Not published, not indexed: issues in generating and finding hospice and palliative care literature
(Mary Ann Liebert, Inc., 2010-01-06)
Not all research work and new knowledge within hospice and palliative care is converted to journal articles and published. Journal indexing does not equate with indexing all contents of all listed journals. There are ...
A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative group
(Mary Ann Liebert, Inc., 2010-11-24)
Background: Palliative medicine has made rapid progress in establishing its scientific and clinical legitimacy, yet the evidence base to support clinical practice remains deficient in both the quantity and quality of ...