Flinders Open Access Research
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Cholinesterase research outreach project (CROP): point of care cholinesterase measurement in an Australian agricultural community
(BioMed Central, 2018-04-02)Abstract Background Australian farmers are routinely exposed to a wide variety of agrichemicals, including herbicides and insecticides. Organophosphate (OP) insecticides ... -
Where to from here? A quality improvement project investigating burns treatment and rehabilitation practices in India
(BioMed Central, 2018-04-03)Abstract Objective To describe the capacity of the Indian healthcare system in providing appropriate and effective burns treatment and rehabilitation services. ... -
Perspectives of primary health care staff on the implementation of a sexual health quality improvement program: a qualitative study in remote aboriginal communities in Australia
(BioMed Central, 2018-04-02)Abstract Background Young people living in remote Australian Aboriginal communities experience high rates of sexually transmissible infections (STIs). STRIVE (STIs in Remote ... -
Evaluation of oxidative stress biomarkers in idiopathic pulmonary fibrosis and therapeutic applications: a systematic review
(BioMed Central, 2018-03-27)Abstract Introduction Idiopathic pulmonary fibrosis (IPF), a fatal lung disease of unknown origin, is characterized by chronic and progressive fibrosing interstitial pneumonia ... -
Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma
(BioMed Central, 2018-04-13)Abstract Background Multidrug resistance-associated protein 1 (MRP1) overexpression plays a major role in chemoresistance in glioblastoma multiforme (GBM) contributing to ... -
Connecting the dots between breast cancer, obesity and alcohol consumption in middle-aged women: ecological and case control studies
(BioMed Central, 2018-04-06)Abstract Background Breast cancer (BC) incidence in Australian women aged 45 to 64 years (‘middle-aged’) has tripled in the past 50 years, along with increasing alcohol ... -
How institutional forces, ideas and actors shaped population health planning in Australian regional primary health care organisations
(BioMed Central, 2018-03-20)Abstract Background Worldwide, there are competing norms driving health system changes and reorganisation. One such norm is that of health systems’ responsibilities for ... -
Encompassing new use cases - level 3.0 of the HUPO-PSI format for molecular interactions
(BioMed Central, 2018-04-11)Abstract Background Systems biologists study interaction data to understand the behaviour of whole cell systems, and their environment, at a molecular level. In order to ... -
Low-frequency and rare variants may contribute to elucidate the genetics of major depressive disorder
(Springer Nature, 2018-03-27)Major depressive disorder (MDD) is a common but serious psychiatric disorder with significant levels of morbidity and mortality. Recent genome-wide association studies (GWAS) on common variants increase our understanding ... -
Hypothesis: The Psychedelic Ayahuasca Heals Traumatic Memories via a Sigma 1 Receptor-Mediated Epigenetic-Mnemonic Process
(Frontiers Media S.A., 2018-04-05)Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and epigenetic regulation. N,N-Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) activates sigma 1 receptor (SIGMAR1) and others. ... -
Predictors of anti-VEGF drug-induced hypertension using different hypertension criteria: a secondary analysis of the COMPARZ study
(Sage Journals, 2018-02-05)Background: There is inconsistency in the criteria used to define anti-vascular endothelial growth factor (VEGF) drug-induced hypertension (AVEGF-HT) in published studies. It is unknown whether specific patient characteristics ... -
Validation of a risk prediction model for Barrett’s esophagus in an Australian population
(Dove Press, 2018-03-28)Background: Esophageal adenocarcinoma is a disease that has a high mortality rate, the only known precursor being Barrett’s esophagus (BE). While screening for BE is not cost-effective at the population level, targeted ... -
Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit
(Wiley, 2018-04-18)Crude oil and hydrocarbon fuel spills are a perennial threat to aquatic environments. Inexpensive and sustainable sorbents are needed to mitigate the ecological harm of this pollution. To address this need, this study ... -
The Experience of Paid Family-Care Workers of People with Dementia in South Korea
(Elsevier Korea LLC, 2018-01-22)Purpose: The South Korean government introduced the universal long-term care insurance program in 2008 that created a new employment category of “paid family-care worker” to assist the elderly with chronic illnesses ... -
The Australian Corneal Graft Registry 2018 Report
(South Australian Health and Medical Research Institute, 2018)The Australian Corneal Graft Registry 2018 Report is still being published and will be made available here shortly. The Australian Corneal Graft Registry (ACGR) opened in May 1985 and has now been operating for 33 ... -
Stability of phenolic compounds and antioxidant capacity of concentrated mulberry juice-enriched dried-minced pork slices during preparation and storage
(Elsevier, 2018-02-09)Functional foods have been of increasing demand due to the growing consumer awareness of the relationship between diet and health. Addition of healthy ingredients to meat products is an important method for development of ... -
Palaeohydrogeology and Transport Parameters Derived from 4He and Cl Profiles in Aquitard Pore Waters in a Large Multilayer Aquifer System, Central Australia
(2017-11-20)A study of chloride and 4He profiles through an aquitard that separates the Great Artesian Basin from the underlying Arckaringa Basin in central Australia is presented. The aquitard separates two aquifers with long water ... -
Magnesium and Human Health: Perspectives and Research Directions
(Hindawi Publishing Corporation, 2018-04-16)Magnesium is the fourth most abundant cation in the body. It has several functions in the human body including its role as a cofactor for more than 300 enzymatic reactions. Several studies have shown that hypomagnesemia ... -
Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
(Hindawi Publishing Corporation, 2017-12-03)Alterations in global DNA methylation are implicated in various pathophysiological processes. The development of simple and quick, yet robust, methods to assess DNA methylation is required to facilitate its measurement and ... -
Understanding child disadvantage from a social determinants perspective
(BMJ Publishing Group, 2017-12-20)Background Child health and developmental inequities exist in all countries. Comprehensive and robust concepts of disadvantage are fundamental to growing an evidence base that can reveal the extent of inequities in childhood, ...
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