Now showing items 458-477 of 658

    • Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2 

      Du, Wei; Forte, Gabriella M; Smith, Duncan; Petersen, Janni (The Royal Society, 2016)
      Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2. Here, we show that a novel phosphorylation of fission ...
    • Physiological augmentation of esophageal distension pressure and peristalsis during conditions of increased esophageal emptying resistance. 

      Brink, Anna G J; Lei, Wei-Yi; Omari, Taher; Singendonk, Maartje M J; Hung, Jui-Sheng; Liu, Tso Tsai; Yi, Chih-Hsun; Chen, Chien-Lin (Wiley, 2017-10-24)
      Background Abdominal compression has been implemented as a provocative maneuver in high‐resolution impedance manometry (HRIM) to “challenge” normal esophageal physiology with the aim of revealing abnormal motor patterns ...
    • Physiological Evidence Consistent with Reduced Neuroplasticity in Human Adolescents Born Preterm 

      Pitcher, Julia B; Riley, Alysha M; Doeltgen, Sebastian; Kurylowicz, Lisa; Rothwell, John C; McAllister, Sue Margery; Smith, Ashleigh E; Clow, Angela; Kennaway, David J; Ridding, Michael C (Society of Neuroscience, 2012-11-12)
      Preterm-born children commonly experience motor, cognitive, and learning difficulties that may be accompanied by altered brain microstructure, connectivity, and neurochemistry. However, the mechanisms linking the altered ...
    • Phytol: A review of biomedical activities 

      Islam, Muhammad Torequl; Ali, Eunus S; Uddin, Shaikh Jamal; Shaw, Subrata; Islam, Md Amirul; Ahmed, Md. Iqbal; Shill, Manik Chandra; Karmakar, Utpal Kumar; Yarla, Nagendra Sastry; Khan, Ishaq N; Billah, Md Morsaline; Pieczynska, Magdalena D; Zengin, Gokhan; Malainer, Clemens; Nicoletti, Ferdinando; Gulei, Diana; Berindan-Neagoe, Ioana; Apostolov, Apostol; Banach, Maciej; Yeung, Andy W K; El-Demerdash, Amr; Xiao, Jianbo; Dey, Prasanta; Yele, Santosh; Jozwik, Artur; Strzalkowska, Nina; Marchewka, Joanna; Rengasamy, Kannan R R; Horbanczuk, Jaroslaw; Kamal, Mohammad Amjad; Mubarak, Mohammad S; Mishra, Siddhartha Kumar; Shilpi, Jamil A; Atanasov, Atanas G (Elsevier, 2018-04-18)
      Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil ...
    • The Pneumococcal Alpha-Glycerophosphate Oxidase Enhances Nasopharyngeal Colonization through Binding to Host Glycoconjugates 

      Mahdi, L K; Higgins, M A; Day, C J; Tiralongo, J; Hartley-Tassell, L E; Jennings, M P; Gordon, David Llewellyn; Paton, A W; Paton, J C; Ogunniyi, A D (Elsevier, 2017-03-03)
      Streptococcus pneumoniae (the pneumococcus) is a major human pathogen, causing a broad spectrum of diseases including otitis media, pneumonia, bacteraemia and meningitis. Here we examined the role of a potential pneumococcal ...
    • Pneumococcal vaccination and otitis media in Australian Aboriginal infants: comparison of two birth cohorts before and after introduction of vaccination 

      Mackenzie, Grant; Carapetis, Jonathan R; Leach, Amanda Jane; Morris, Peter Stanley (BioMed Central Ltd., 2009)
      Aboriginal children in remote Australia have high rates of complicated middle ear disease associated with Streptococcus pneumoniae and other pathogens. We assessed the effectiveness of pneumococcal vaccination for prevention ...
    • Point-of-care in Aboriginal hands 

      Jones, Richard; Mazzachi, Beryl C; Shephard, Mark Douglas (Aboriginal and Islander Health Worker Journal, 2002)
      Diabetes, kidney disease and heart disease (all chronic diseases) are among the most serious health problems facing Aboriginal people today. The point-of-care program has a broad chronic disease focus that (a) looks for ...
    • Point-of-care testing and creatinine measurement 

      Shephard, Mark Douglas (Australasian Association of Clinical Biochemists, 2011)
      This paper reviews the current status of point-of-care testing (PoCT) devices that are available for measuring whole blood or serum/plasma creatinine globally and within Australasia. Information on non-analytical specifications ...
    • Point-of-care testing comes of age in Australia 

      Shephard, Mark Douglas (NPS MedicineWise, 2010)
      A wide range of point-of-care tests is available and being used in both hospital and community settings for acute and chronic illnesses. There have been significant improvements in device technology as well as advances in ...
    • Point-of-care testing in the Aboriginal community 

      Shephard, Mark Douglas (Australian Institute of Medical Scientists, 2003)
      This article documents experiences working in the field of Aboriginal health. The principle focus of the work is the application of Point-of-Care (POC) technology for the early detection and management of chronic diseases ...
    • Point-of-care testing in the Indigenous rural community 

      Shephard, Mark Douglas (Australasian Association of Clinical Biochemists, 2004)
      This paper describes three health programs - the 'Umoona Kidney Project', the national 'QAAMS' Program for point-of-care HbA1c testing and the 'Point-of-Care in Aboriginal Hands' Program. The common feature these models ...
    • The politics of participation 

      Dwyer, Judith Margaret (Public Health Association of Australia, 1989-03)
      Community participation in health policy, planning and services is a central theme in the current exploration of community development methods for the promotion of health. Participation is an idea in good currency, but ...
    • Post-stroke sleep-disordered breathing - pathophysiology and therapy options 

      Stevens, David; Martins, Rodrigo Tomazini; Mukherjee, Sutapa; Vakulin, Andrew (Frontiers Media, 2018-02-26)
      Sleep-disordered breathing (SDB), encompassing both obstructive and central sleep apnea, is prevalent in at least 50% of stroke patients. Small studies have shown vast improvements in post-stroke functional recovery ...
    • The Potential Benefits of Applying Recent Advances in Esophageal Motility Testing in Patients with Esophageal Atresia 

      Rommel, Nathalie; Rayyan, Maissa; Schreerens, Charlotte; Omari, Taher (Frontiers Media S.A., 2017-06-21)
      Infants and children with esophageal atresia commonly present with swallowing dysfunction or dysphagia. Dysphagia can lead to a range of significant consequences such as aspiration pneumonia, malnutrition, dehydration, and ...
    • A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis 

      Thuan, Duong Thi Bich; Zayed, Hatem; Eid, Ali H; Abou-Saleh, Haissam; Nasrallah, Gheyath K; Mangoni, Arduino Aleksander; Pintus, Gianfranco (Frontiers Media, 2018-09-19)
      Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
    • PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa 

      Burr, Lucy D; Rogers, Geraint B; Chen, Alice; Taylor, Steven L; Bowler, Simon D; Keating, Rebecca L; Martin, Megan L; Hasnain, Sumaira Z; McGuckin, Michael A (Public Library of Science, 2018-08-16)
      Background Chronic airway inflammation in conditions such as cystic fibrosis (CF) and non-CF bronchiectasis is characterised by a predominant neutrophilic inflammatory response, commonly due to the presence of pathogenic ...
    • Practice change in chronic conditions care: an appraisal of theories 

      Harris, Melanie; Lawn, Sharon Joy; Morello, Andrea; Battersby, Malcolm Wayne; Ratcliffe, Julie; McEvoy, Ronald Douglas (BioMed Central, 2017-02-28)
      Background Management of chronic conditions can be complex and burdensome for patients and complex and costly for health systems. Outcomes could be improved and costs reduced if proven clinical interventions were better ...
    • Practice intentions at entry to and exit from medical schools aspiring to social accountability: findings from the Training for Health Equity Network Graduate Outcome Study 

      Larkins, Sarah; Johnston, Karen; Hogenbirk, John C; Willems, Sara; Elsanousi, Salwa; Mammen, Marykutty; Van Roy, Kaatje; Iputo, Jehu; Cristobal, Fortunato L; Greenhill, Jennene Ann; Labarda, Charlie; Neusy, Andre-Jacques (BMC, 2018-11-13)
      Background Understanding the impact of selection and medical education on practice intentions and eventual practice is an essential component of training a fit-for-purpose health workforce distributed ...
    • Practice Nurses as Case Managers in a Collaborative Care Model for Managing Depression among Patients with Heart Disease or Diabetes: The D_Tect and TrueBlue Studies in Primary Care 

      Morgan, Mark Andrew; Reddy, Prasuna; Coates, Michael; Leahy, Robert; Schlicht, Kate; Dunbar, James Anthony (Australian Rural Health Education Network, 2010)
      A successful feasibility study called D_TECT (Depression Treatment Evaluation Care Team) used a collaborative approach to detect, monitor and treat depression among patients with existing type 2 diabetes mellitus (T2DM) ...
    • Predicting success in medical school: a longitudinal study of common Australian student selection tools 

      Sladek, Ruth; Bond, Malcolm James; Frost, Linda K; Prior, Kristy N (BioMed Central, 2016)
      Background: Medical student selection and assessment share an underlying high stakes context with the need for valid and reliable tools. This study examined the predictive validity of three tools commonly used in ...