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    • A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm 

      Casolari, Debora A; Nguyen, Tran; Butcher, Carolyn M; Iarossi, Diana G; Hahn, Christopher N; Bray, Sarah C E; Neufing, Petra J; Parker, Wendy T; Feng, Jinghua; Maung, Kyaw Ze Ya; Wee, A; Vidovic, Ljiljana; Kok, Chung H; Bardy, Peter G; Branford, Susan; Lewis, Ian D; Lane, Steven W; Scott, Hamish S; Ross, David Morrall; D'Andrea, Richard J (Nature Publishing Group, 2017-05-26)
      We describe a novel ERBB1/EGFR somatic mutation (p. C329R; c.985 T > C) identified in a patient with JAK2V617F Polycythaemia Vera (PV). This substitution affects a conserved cysteine residue in EGFR domain 2 and leads to ...