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    • The preventative role of exogenous melatonin administration to patients with advanced cancer who are at risk of delirium: study protocol for a randomized controlled trial 

      Harvey-Bush, Shirley; Lacaze-Masmonteil, Nathalie; McNamara-Kilian, Marie Theresa; MacDonald, Alistair Richard; Tierney, Sallyanne; Momoli, Franco; Agar, Meera Ruth; Currow, David Christopher; Lawlor, Peter Gerard (Bush SH, Lacaze-Masmonteil N, McNamara-Kilian MT, et al. The preventative role of exogenous melatonin administration to patients with advanced cancer who are at risk of delirium: study protocol for a randomized controlled trial. Trials. 2016;17:399. doi:10.1186/s13063-016-1525-8., 2016)
      Background Delirium is a very common and distressing neuropsychiatric syndrome in palliative care. Increasing age, the presence of dementia and advanced cancer are well-known predisposing risk factors for delirium development. ...