Now showing items 1-2 of 2

    • Complex structural rearrangements are present in high-grade dysplastic Barrett’s oesophagus samples 

      Newell, Felicity; Patel, Kalpana; Gartside, Michael; Krause, Lutz; Brosda, Sandra; Aoude, Lauren G; Loffler, Kelly A; Bonazzi, Vanessa F; Patch, Ann-Marie; Kazakoff, Stephen H; Holmes, Oliver; Xu, Qinying; Wood, Scott; Leonard, Conrad; Lampe, Guy; Lord, Reginald V; Whiteman, David C; Pearson, John V; Nones, Katia; Waddell, Nicola; Barbour, Andrew P (BioMed Central, 2019-02-04)
      Abstract Background Oesophageal adenocarcinoma (EAC) incidence is increasing and has a poor survival rate. Barrett’s oesophagus (BE) is a precursor condition that is associated with EAC and often occurs in conjunction ...
    • Copy number profiles of paired primary and metastatic colorectal cancers 

      Kawamata, Futoshi; Patch, Ann-Marie; Nones, Katia; Bond, Catherine; McKeone, Diane; Pearson, Sally-Ann; Homma, Shigenori; Liu, Cheng; Fennell, Lochlan; Dumenil, Troy; Hartel, Gunter; Kobayasi, Nozomi; Yokoo, Hideki; Fukai, Moto; Nishihara, Hiroshi; Kamiyama, Toshiya; Burge, Matthew E; Karapetis, Christos Stelios; Taketomi, Akinobu; Leggett, Barbara A; Waddell, Nicola; Whitehall, Vicki L (2017-12-15)
      Liver metastasis is the major cause of death following a diagnosis of colorectal cancer (CRC). In this study, we compared the copy number profiles of paired primary and liver metastatic CRC to better understand how the ...