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dc.contributor.authorLew, Charles Chin Han
dc.contributor.authorWong, Gabriel Jun Yung
dc.contributor.authorCheung, Ka Po
dc.contributor.authorChua, Ai Ping
dc.contributor.authorChong, Mary Foong Fong
dc.contributor.authorMiller, Michelle Deanne
dc.date.accessioned2018-03-22T03:58:52Z
dc.date.available2018-03-22T03:58:52Z
dc.date.issued2017-12-23
dc.identifier.citationLew, C.C.H.; Wong, G.J.Y.; Cheung, K.P.; Chua, A.P.; Chong, M.F.F.; Miller, M. Association between Malnutrition and 28-Day Mortality and Intensive Care Length-of-Stay in the Critically ill: A Prospective Cohort Study. Nutrients 2018, 10, 10.en
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/2328/37800
dc.descriptionLicensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.description.abstractThere is limited evidence for the association between malnutrition and mortality as well as Intensive Care Unit length-of-stay (ICU-LOS) in critically ill patients. We aimed to examine the aforementioned associations by conducting a prospective cohort study in an ICU of a Singapore tertiary hospital. Between August 2015 and October 2016, all adult patients with ≥ 24 h of ICU-LOS were included. The 7-point Subjective Global Assessment (7-point SGA) was used to determine patients’ nutritional status within 48 h of ICU admission. Multivariable regressions were conducted in two ways: (1) presence versus absence of malnutrition, and (2) dose-dependent association for each 1-point decrease in the 7-point SGA. There were 439 patients of which 28.0% were malnourished, and the 28-day mortality rate was 28.0%. Malnutrition was associated with an increased risk of 28-day mortality (adjusted Relative Risk 1.33 (95% Confidence Interval: 1.05–1.69)), and this risk increased with a greater degree of malnutrition (adjusted Relative Risk 1.08 (95% Confidence Interval: 1.00–1.16) for each 1-point decrease in the 7-point SGA). No significant association was found between malnutrition and ICU-LOS. The results of this study indicated a clear association between malnutrition and higher 28-day mortality in critically ill patients. The association between malnutrition and ICU-LOS could not be replicated and hence requires further evaluation. View Full-Texten_US
dc.language.isoen
dc.publisherMDPIen
dc.rights© 2017 by the authors.en
dc.subjectmalnutrition;
dc.subjectnutritional assessment
dc.subjectmortality;
dc.subjectength-of-stay
dc.subjectcritical illness
dc.titleAssociation between Malnutrition and 28-Day Mortality and Intensive Care Length-of-Stay in the Critically ill: A Prospective Cohort Studyen
dc.typeArticleen
dc.identifier.doihttps://doi.org/10.3390/nu10010010en
dc.rights.holderthe authors.en
dc.rights.licenseCC-BY
local.contributor.authorOrcidLookupLew, Charles Chin Han: https://orcid.org/0000-0001-6410-3859


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