Now showing items 1-4 of 4

    • Common Sequence Variation in the VEGFC Gene Is Associated with Diabetic Retinopathy and Diabetic Macular Edema 

      Kaidonis, Georgia; Burdon, Kathryn Penelope; Gillies, Mark; Abhary, Sotoodeh; Essex, Rohan; Chang, John H; Pal, Bishwanath; Pefkianaki, Maria; Daniell, Maria; Lake, Stewart; Petrovsky, Nikolai; Hewitt, Alex W; Jenkins, Alicia; Lamoureux, Ecosse L; Gleadle, Jonathan; Craig, Jamie E (Elsevier, 2015-06-11)
      Purpose To investigate associations between single nucleotide polymorphisms (SNPs) in the VEGFC gene and the development of diabetic retinopathy (DR) in white patients with type 1 diabetes mellitus (T1DM) or type 2 ...
    • Genetic study of Diabetic Retinopathy: recruitment methodology and analysis of baseline characteristics 

      Kaidonis, Georgia; Abhary, Sotoodeh; Daniell, Mark; Gillies, Mark; Fogarty, Rhys Daniel; Petrovsky, Nikolai; Jenkins, Alicia; Essex, Rohan; Chang, John H; Pal, Bishwanath; Hewitt, Alex W; Burdon, Kathryn Penelope; Craig, Jamie E (Wiley-Blackwell, 2013-09-30)
      BACKGROUND: Diabetic retinopathy (DR) is a blinding disease of increasing prevalence, caused by a complex interplay of genetic and environmental factors. Here we describe the patient recruitment methodology, case and control ...
    • Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy 

      Graham, Patricia S; Kaidonis, Georgia; Abhary, Sotoodeh; Gillies, Mark; Daniell, Mark; Essex, Rohan; Chang, John H; Lake, Stewart; Pal, Bishwanath; Jenkins, Alicia; Hewitt, Alex W; Lamoureux, Ecosse L; Hykin, Philip G; Petrovsky, Nikolai; Brown, Matthew A; Craig, Jamie E; Burdon, Kathryn Penelope (BioMed Central, 2018-05-08)
      Abstract Background Diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) are sight-threatening complications of diabetes mellitus and leading causes ...
    • Promoter polymorphism at the tumour necrosis factor/lymphotoxin-alpha locus is associated with type of diabetes but not with susceptibility to sight-threatening diabetic retinopathy 

      Kaidonis, Georgia; Craig, Jamie E; Gillies, Mark; Abhary, Sotoodeh; Essex, Rohan; Chang, J H; Pal, Bishwanath; Pefkianaki, Maria; Daniell, Mark; Lake, Stewart; Petrovsky, Nikolai; Burdon, Kathryn Penelope (SAGE Publications, 2016-01-28)
      AIM: To investigate, in a large cohort of 2494 individuals with diabetes mellitus, whether functional single nucleotide polymorphisms in the promoter region of tumour necrosis factor (TNF) and lymphotoxin-alpha (LTA) ...