Now showing items 1-10 of 38
A Comparison of Lamellar and Penetrating Keratoplasty Outcomes: A Registry Study
Novel therapeutic approaches for corneal disease
(Discovery Medicine, 2013-05-24)
Congenital and acquired corneal opacities, and diseases of the ocular surface, are blinding conditions that impose physical, psychological, and financial constraints upon the sufferer. In the past, corneal and corneal ...
The influence of Australian eye banking practices on corneal graft survival
(Australasian Medical Publishing Company, 2013-08-19)
Donor corneas transported interstate exhibited poorer survival after transplantation than those retrieved and grafted locally. Higher proportions of emergency procedures involving transported corneas did not account for ...
Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions
(Association for Research in Vision and Ophthalmology, 2016)
PURPOSE: The species cross-reactivity of the monoclonal antibodies infliximab, bevacizumab, and an anti-VEGF-B antibody, 2H10, in humans and rodents was determined. METHODS: The binding of infliximab to human, mouse, and ...
A comparison of endothelial and penetrating keratoplasty outcomes following failed penetrating keratoplasty: a registry study
(BMJ Publishing Group, 2016)
Purpose To compare graft survival and visual outcomes for endothelial keratoplasty (EK) after a first penetrating keratoplasty (PK), with outcomes of repeat PK after a first PK. Methods 400 eyes with a second graft (65 ...
Influence of format on in vitro penetration of antibody fragments through porcine cornea
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 2005-09)
AIM: Antibody fragments, appropriately formulated, can penetrate through the ocular surface and thus have potential as therapeutic agents. The aim was to investigate the influence of protein fragment format on the kinetics ...
The outcome of corneal transplantation in infants, children, and adolescents
OBJECTIVE: To examine factors affecting penetrating corneal graft survival and visual outcomes in patients aged less than 20 years. DESIGN: Large prospective, cohort study. PARTICIPANTS: Records of 14 865 followed ...
A simple corneal perfusion chamber for drug penetration and toxicity studies
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 2001-04)
AIMS: Corneal perfusion chambers are important tools in the development and assessment of ophthalmic drugs. The aim of this study was to design and test a modified perfusion chamber suitable for topical application of drugs ...
Influence of advanced recipient and donor age on the outcome of corneal transplantation. Australian Corneal Graft Registry.
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 1997-10)
AIMS: The aims of this study were to examine the influence of advanced recipient and donor age on the long term outcome of corneal transplantation. METHODS: Records of 1036 penetrating corneal grafts in recipients aged > ...
Apoptosis is a prominent feature of acute anterior uveitis in the Fischer 344 rat
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 2000-02)
AIMS: To examine the hypothesis that apoptosis of infiltrating cells contributes to spontaneous resolution of uveitis in clinically relevant rodent models. METHODS: Experimental melanin induced uveitis (EMIU) was induced ...