Now showing items 1-9 of 9
A Comparison of Lamellar and Penetrating Keratoplasty Outcomes: A Registry Study
Macular hypoplasia in congenital disorder of glycosylation type 1a
(S. Karger, Basel, 2012)
Congenital disorders of glycosylation are a rare group of metabolic disorders that can result in multiorgan disease. This article describes a novel finding of macular hypoplasia in congenital disorders of glycosylation type 1a.
Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma
(Nature Publishing Group, 2014-10)
Primary open-angle glaucoma (POAG) is a major cause of irreversible blindness worldwide. We performed a genome-wide association study in an Australian discovery cohort comprising 1,155 cases with advanced POAG and 1,992 ...
Patient-centred measurement in ophthalmology - a paradigm shift
(BioMed Central - http://www.biomedcentral.com, 2006-06)
Ophthalmologists and researchers in ophthalmology understand what a rapidly evolving field ophthalmology is, and that to conduct good research it is essential to use the latest and best methods. In outcomes research, one ...
A cross-ethnicity investigation of genes previously implicated in primary angle closure glaucoma
(Emory Eye Centre, 2012)
Purpose: To investigate the underlying genetic variation between candidate genes and primary angle closure glaucoma (PACG) in both Nepalese and Australian populations. Methods: A total of 213 patients with PACG (106 Nepalese ...
The related transcriptional enhancer factor-1 isoform, TEAD4 216, can repress vascular endothelial growth factor expression in mammalian cells
(Public Library of Science, 2012-06-22)
Increased cellular production of vascular endothelial growth factor (VEGF) is responsible for the development and progression of multiple cancers and other neovascular conditions, and therapies targeting post-translational ...
Visual Performance in Patients with Neovascular Age-Related Macular Degeneration Undergoing Treatment with Intravitreal Ranibizumab
(Hindawi Publishing Corporation, 2013)
Purpose. To assess visual function and its response to serial intravitreal ranibizumab (Lucentis, Genentech) in patients with neovascular age-related macular degeneration (nv-AMD). Methods. Forty-seven eyes of 47 patients ...
A Proposed Minimum Standard Set of Outcome Measures for Cataract Surgery
(American Medical Association, 2015-08-20)
Importance Aligning outcome measures for cataract surgery, one of the most frequently performed procedures globally, may facilitate international comparisons that can drive improvements in the outcomes most meaningful to ...