Now showing items 1-5 of 5
Influence of format on in vitro penetration of antibody fragments through porcine cornea
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 2005-09)
AIM: Antibody fragments, appropriately formulated, can penetrate through the ocular surface and thus have potential as therapeutic agents. The aim was to investigate the influence of protein fragment format on the kinetics ...
In vitro adenovirus mediated gene transfer to the human cornea
(BMJ Publishing Group - http://bjo.bmjjournals.com/, 2005-06)
BACKGROUND/AIMS: Replication deficient adenovirus is an efficient vector for gene transfer to the cornea. The aim was to optimise the transduction of human corneal endothelium with adenoviral vectors and to measure transgene ...
Expression of an anti-CD4 single-chain antibody fragment from the donor cornea can prolong corneal allograft survival in inbred rats
(BMJ Group, 2012-11-21)
To investigate whether expression of an anti-CD4 antibody fragment (scFv) by a lentivector-transduced donor cornea can prolong rat corneal allograft survival. Methods Inbred Fischer 344 rats received penetrating corneal ...
The inﬂuence of cervical and thoracic lymphadenectomy on corneal allograft rejection in inbred rats
(BMJ Group, 2011-11-23)
Aim To investigate the site of alloantigen presentation in the rat following orthotopic corneal transplantation. Methods Adult inbred Fischer 344 rats received penetrating corneal allografts from inbred Wistar Furth donors ...